Previous studies showed that the membrane structure of sEVs is capable of protecting their RNA cargoes from degradation by RNase; hence, co-treatment with Triton X-100 and RNase rapidly degraded miRNA contents in sEVs49. Consistent with this, whereas intact young sEVs improved mitochondrial ...
(typical terms: chromosome organization, chromatin assembly or disassembly, chromatin remodeling, histone ubiquitination, histone H3 deacetylation and regulation of histone methylation) and ‘organelle assembly and disassembly’ (typical terms: nuclear membrane organization, organelle disassembly, protein–lipid ...
AIF can be released from the mitochondria on outer mitochondrial membrane permeabilization and shift to the nucleus to promote nuclear condensation and ultimately DNA damage. Also, DIABLO and HTRA2 can trigger apoptosis by counteract the activity of IAPs by a caspase-independent path. These data ...
As shown in Figure 3B, NPM-ALK expression (nuclear green staining) was restricted to B220/CD45R−cells (B220/CD45R+ cells showed only a red membrane staining) present in the T-cell areas of splenic germinal centers, suggesting that NPM-ALK was largely restricted to T lymphocytes. Download...
To further validate the interaction of aptamer H1 and H11 with C1Q, we performed a filter retention assay (Fig. 3a). Radioactively labelled H1 and H11 were incubated with increasing concentrations of puri- fied C1Q and subsequently passed through a nitrocellulose membrane. The amount of ssODN ...
[eClalnua2li+anr]ti)craainclcemiluluamlmacrmoCnaalci2ea+nnstctroearltlieso.inTse(nm[oCrpamo2+raa]llriyy~m1o pmaienMntia)niangneoddf calcium ion channels activation of various in the signal cell membrane or the ER membrane transduction pathways that regulate leads to a sharp rise cell ...
et al. Characterization of phospholipase C activity at h5-HT2C compared with h5-HT2B receptors: influence of novel ligands upon membrane-bound levels of 3Hphosphatidylinositolss. Naunyn Schmiedebergs Arch Pharmacol 365, 242–252 (2002). 25. Herget, J., Suggett, A. J., Leach, E. & Barer,...
Overall, changes in shape (from spindle to round), cell detachment, shrinkage, and membrane ruptures were observed. Cell cycle: All four studies [36,72,75,79] investigating changes in cell cycles employed FACS assay. Chang et al. [36] reported that CAP caused cell cycle arrest in the ...
cancers Article Plasma Membrane Ca2+ ATPase Isoform 4 (PMCA4) Has an Important Role in Numerous Hallmarks of Pancreatic Cancer Pishyaporn Sritangos 1 , Eduardo Pena Alarcon 1, Andrew D. James 2, Ahlam Sultan 3, Daniel A. Richardson 1 and Jason I. E. Bruce 1,* 1 Division of Cancer ...
antioxidants Review The Plasma Membrane: A Platform for Intra- and Intercellular Redox Signaling Daniela E. Nordzieke 1,* and Iria Medraño-Fernandez 2,* 1 Institute of Microbiology and Genetics, Department of Genetics of Eukaryotic Microorganisms, Georg August University Göttingen, Grisebachstr. ...