tubular cell sloughing, and loss of nuclei, that reflect the morphologic responses of the tubules to a diverse range of insults8,9,10. ATI stands as a hallmark in the diagnosis of AKI but also manifests in the context of CKD10. Episodes of ATI and ...
CCL28 has been found to induce apoptosis in decidual stromal cells, and a higher expression of the receptors of CCL28 (CCR3, CCR10), in these cell populations in spontaneous abortion is displayed prior to a pro-inflammatory stimulation58. Interestingly, in mouse studies, CCL28 has been shown...
Image-guided thermal ablation of tumor increases the plasma level of interleukin-6 and interleukin-10: is plasma level of interleukin-6 a surrogate for immunogenic cell death?ICD, immunogenic cell deathICI, immune checkpoint inhibitorIL, interleukin...
The median age of diagnosis for clonal plasma cell and myeloid disorders was 65 and 69 years, respectively. A small number of patients had tMN due to chemotherapy or radiation received for autoimmune disease (n = 2), antecedent solid tumor (n = 1), or monoclonal gammopathy (n = 1; see...
Thus, our data suggest that, in MM and PDAC, treatment with PALM activates ICD; therefore, if this system is properly validated in larger cell line panels andin vivomodels, PALM produced with O2, could serve as an ICD inducer that can activate the innate immune system to target these tumou...
(n = 847), we assessed the association between cord, early childhood plasma adiponectin and the risk of developing ASD. ASD was defined based on ICD codes of physician diagnosis. Cord adiponectin levels were inversely associated with ASD risk (aOR 0.50; 95% CI 0.33, 0.77), independent ...
tumor or currently suffering from any cancer/tumor; (7) any gastrointestinal diseases or non-gastrointestinal acute disease at the time of enrollment; (8) oral or intravenous antibiotics within the last 6 weeks; (9) use of insulin or corticosteroids at the time of enrollment; (10) long-term...
CXCL14 showed the greatest predictive importance. The levels of CXCL14 expression were closely linked to some clinicopathologic factors, including tumor-node-metastasis stage, tissue differentiation, and tumor size, which have heretofore been noted as possible predictors for the early recurrence and dea...
1i, S1f-g), inhibiting tumor cell growth (Fig. 1d and e), and triggering cancer cell death. Download: Download high-res image (1MB) Download: Download full-size image Fig. 2. Experimental evidence showing the essential role of EGFR signaling in the selectivity of PAM against TNBC cells ...
There is substantial evidence that higher levels of inflam- matory biomarkers, such as tumor necrosis factor-a, various interleukins and transforming growth factor-b are present in major depression as well as AD.71,72 Our analyses did not find any association between depressive symptoms and these...