tubular cell sloughing, and loss of nuclei, that reflect the morphologic responses of the tubules to a diverse range of insults8,9,10. ATI stands as a hallmark in the diagnosis of AKI but also manifests in the context of CKD10. Episodes of ATI and ...
There is substantial evidence that higher levels of inflam- matory biomarkers, such as tumor necrosis factor-a, various interleukins and transforming growth factor-b are present in major depression as well as AD.71,72 Our analyses did not find any association between depressive symptoms and these...
1i, S1f-g), inhibiting tumor cell growth (Fig. 1d and e), and triggering cancer cell death. Download: Download high-res image (1MB) Download: Download full-size image Fig. 2. Experimental evidence showing the essential role of EGFR signaling in the selectivity of PAM against TNBC cells ...
PALM) that might impact cell proliferation, as other authors have already demonstrated27,62, by inducing cell death via ICD. In the two cancer models, PDAC and MM, after preliminarily establishing the optimal conditions for preparing PALM, we characterized the antiproliferative effectiveness...
BRI3, a novel gene, participates in tumor necrosis factor-alpha-induced cell death. Biochem. Biophys. Res. Commun. 2003, 311, 518–524. [CrossRef] [PubMed] 40. Choi, S.C.; Kim, J.; Kim, T.H.; Cho, S.Y.; Park, S.S.; Kim, K.D.; Lee, S.H. Cloning and characterization...
Mol. Cell. Proteom. 20, 100168 (2021). Article CAS Google Scholar Zhong, W. et al. Next generation plasma proteome profiling to monitor health and disease. Nat. Commun. 12, 2493 (2021). Article CAS PubMed PubMed Central Google Scholar Ho-Le, T. P. et al. Genetic prediction of ...
Interestingly, mir-17–92-deficiency in B cells leads to enhanced homing of plasma cells to the bone marrow during T-cell-dependent immune response and selectively impairs IgG2c production. Mechanistically, mir-17–92 directly represses the expression of Sphingosine 1-phosphate receptor 1 and ...
(HMGB1) on the cell surface of CT26 colon-cancer cells (Fig.7a,c,e) using flow cytometry. The H2O2-degrading enzyme catalase abolished this increase in all groups (Supplementary Fig.S4). Strikingly, our treatment induced an upregulated of ICD-markers also in MC38 and PDA6606 tumor cells,...
However, it is generally presumed that low dose plasma treatment stimulates cell viability and enhances proliferation, differentiation, and migration, while high doses should induce cell apoptosis [26]. Plasma devices used in clinical practice are designed to avoid danger to healthy cells. They ...
A bead-based assay (LEGENDplex; BioLegend) was used to quantify the following 13 cytokines: interferon (IFN-)α, IFN-γ, interleukin (IL)1β, IL6, IL8, IL10, IL12p70, IL17A, IL18, IL23, IL33, monocyte chemoattractant protein 1 (MCP1), and tumor necrosis factor (TNF)α. Cell cul...