Plasma cell myeloma - a unique case presenting as thyroid plasmacytoma and mimicking of medullary carcinoma: how to avoid pitfall in aspiration cytologydoi:10.24911/ejmcr/173-1638536657MULTIPLE myelomaMEDULLARY thyroid carcinomaNEEDLE biopsyULTRASONIC imagingIMMUNOHISTOCHEMISTRY...
Plasma cell neoplasmsare a group of entities characterized by the neoplastic proliferation of a single clone ofplasma cells, and can present as a single lesion (solitary plasmacytoma) or as multiple lesions (multiple myeloma [MM]).1In the brain, the involvement is mostly of theleptomeninges, wi...
Fig. 1. Plasma cell cytology. Comparison of asynchrony score (A) and immaturity score (B) for plasma cells from patients with plasma cell leukemia (L), multiple myeloma (M), and without plasma cell malignancy (N). Postmortem examination was carried out in eight cases. Leukemic infiltration ...
fine-needle aspiration cytologypituitaryPlasma cell neoplasms (plasma cell dyscrasias) are a group of entities characterized by the neoplastic proliferation of a single clone of plasma cells, typically producing a monoclonal immunoglobulin. These tumors can manifest as multiple myeloma, monoclonal gammopathy...
Plasma cell myeloma is a more complex neoplasm than suggested by the relative uniformity of its dominant plasma cells, which represent the terminal stage of normal B-cell differentiation. Phenotypic, molecular, and cellular genetic data favor the presence of a myeloma stem cell early in hematopoietic...
Liquid biopsy by analysis of circulating myeloma cells and cell-free nucleic acids: a novel noninvasive approach of disease evaluation in multiple myeloma Shuchan Li Enfan Zhang Zhen Cai Biomarker Research (2023) Decoding cell-type contributions to the cfRNA transcriptomic landscape of liver cance...
Multiple myeloma disrupts normal blood cell production, requiring earlydetection due to the increased risk of bone metastases. Although various artificialintelligence (AI) methods have been developed to assist pathologists, theyoften lack comprehensive metrics to measure both detection and segmentationerrors....
1 Depending on the clinical presentations and laboratory findings, plasma cell neoplasms, according to the 2022 World Health Organization (WHO) Classification, are usually classified as monoclonal gammopathies, light or heavy chain diseases, mass-forming plasmacytoma, plasma cell myeloma, or plasma ...
The differential diagnosis with plasma cell myeloma t(11;14)(q13;q32) positive should be also considered.49,50Recently, several studies have investigated SOX11 immunohistochemical expression in 56 cases of plasmacytoma/myeloma (73% cyclin D1-positive and 27% cyclin D1-negative) including 12 cyclin...
Intranuclear inclusions in Bence Jones Lambda plasma cell myeloma A patient with plasma cell myeloma producing only Bence Jones lambda protein was found to have pale intranuclear inclusions in the majority of the bone marrow plasma cells. These inclusions, previously undescribed in myeloma patients pro...