BACKGROUND Plasma cell leukemia(PCL) is diagnosed by the presence of an absolute plasma cell count of > 2 脳 109/L or 20% plasma cells in the peripheral blood. Because the incidence of PCL is relatively low, our case report study presents a rare opportunity to describe the clinical and ...
Circulating plasma cells can be seen in ~15% of cases, usually small numbers not meeting criteria for plasma cell leukemia (> 2 x 109/L or 20% of the leukocyte count) Peripheral smear images Contributed by Genevieve M. Crane, M.D., Ph.D. Peripheral blood rouleaux Rouleaux formation Image...
The current definition of plasma cell leukemia (PCL)— ≥ 20% circulating plasma cells (CPCs) on peripheral smear and plasma cell count ≥ 2 × 109/L—may be too stringent. We reviewed outcomes of 176 multiple myeloma (MM) patients diagnosed between 1971 and 2016, and who ha...
Plasma cell leukemia (PCL) is a rare and aggressive form of plasma cell dyscrasia, often presenting as a variant of multiple myeloma (MM). It is characterized by the presence of ≥5% circulating plasma cells in peripheral blood, either as a primary or secondary manifestation of MM. METHODS...
Leukemia (leukapheresis) (for acute debulking only) including mantle cell lymphoma (mantle cell leukemia) if white blood cells count is greater than 100,000/µL; or Myasthenia gravis, in persons with any of the following: Acute, short-term benefit is critical because of a sudden worsening of...
Primary plasma cell leukemia (pPCL) is the most aggressive form of the plasma cell dyscrasias. It is defined by the presence of > 2 × 109/L peripheral blood plasma cells or plasmacytosis accounting for > 20% of the differential white cell count, and does not arise from preexisting multipl...
The case was diagnosed as plasma cell leukemia due to the high percentage of plasma cells in the peripheral blood.7 Depending on CD138 for diagnosis of plasma cell neoplasm can also raise some other challenges, such as differential diagnosis of Plasmablastic lymphoma. The latter are usually ...
A Case of CD138−/CD19+/CD4+ IgD Plasma Cell Leukemia. Cytometry Part B 2014;00B:000-000. Author Information IJC, Hospital Germans Trias i Pujol, Hematology Laboratory and Pathology Service, Badalona, Spain *Correspondence to: Jordi Juncà; IJC, Hospital Germans Trias i Pujol, Hematology...
An insightful observation was made upon the microscopic examination of CB smear preparations that there was an immature appearing white cell population that resembled blast cells. Further research into this cell population revealed that this blastlike population was in fact a benign hematopoietic ...
Peripheral blood and bone marrow smear showed marked plasma cell proliferation mimicking plasma cell leukemia. However, flow cytometric analysis showed that plasma cells were of polyclonal origin and M-protein was not detected by immunofixation of serum protein. Elevations of soluble interleukin 2 ...