says Wang. "Finding them fills a major gap in the brassinosteroid signaling pathway and may have major implications for our understanding of other signaling processes in plants as well. The plant genome codes for many hundreds of receptors at the cell surface, but a major missing link is their...
c The estradiol inducible integrase construct is composed of p35S:XVE (transcriptional activator composed of a DNA-binding domain of LexA, the transcription activation domain of VP16, and the regulatory region of the human estrogen receptor66;) and pLexA-minimal 35S driving expression of PhiC31....
2. In plants, however, the molecular mechanisms of how signal perception is transduced to MAPK activation remain elusive1. Here we report that pathogen-secreted proteases activate a previously unknown signalling pathway inArabidopsis thalianainvolving the Gα, G...
The effects of soil and Trifolium repens (white clover) on the fate of estrogen. J Environ Sci Health Part B. 2009;44(3):284–91. Article CAS Google Scholar Rogers M, Noble C, Halloran G, Nicolas M. Selecting for salt tolerance in white clover (Trifolium repens): chloride ion ...
PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. Recently, using the medial forebrain bundle (MFB) 6-hydroxydopmaine (6-OHDA) lesion rat model of Parkinson's disease (PD), we have demonstrated that ...
A Plant Natural Compound(Shikonin) with 4-Hydroxytamoxifen Synergistically Inhibits the Proliferation of Breast Cancer Cells through Activating Apoptosis Signaling Pathway in Vitro and in Vivo 4-Hydroxytamoxifen(4-OHT) is the first line of endocrine therapy for estrogen receptor positive(ER+) breast ca...
Evidence for a Mitochondrial Regulatory Pathway Defined by Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α, Estrogen-Related Receptor-α, an... In keeping with the role of peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1 alpha on energy expenditure, we demonstrate a st...
Plants and microbes communicate to collaborate to stop pests, scavenge nutrients, and react to environmental change. Microbiota consisting of thousands of species interact with each other and plants using a large chemical language that is interpreted by
In addition, significantly lower levels of circulating miR159 were associated with a neg- ative status of estrogen receptor (ER) or progesterone receptor (PR) expression in the tumor, whereas the ex- pression of HER2 and inflammation status in the tumor were not associated with miR159 levels (...
if the extract affected estrogen metabolism, a key mechanism in breast cancer. As a compound in hop extract, 6-prenylnarigenin (6-PN) enhances the detoxification pathway in these breast cells, and increased activity of this detoxification pathway is associated with a lower risk of breast cancer...