Treatments of Negative Symptoms in Schizophrenia: Meta-Analysis of 168 Randomized Placebo-Controlled Trials Objectives: Existing treatments for schizophrenia can improve positive symptoms, but it is unclear if they have any impact on negative symptoms. This meta-......
Metrics Abstract Antidepressant–placebo response-differences (RDs) in controlled trials have been declining, potentially confounding comparisons among older and newer drugs. For clinically employed antidepressants, we carried out a meta-analytic review of placebo-controlled trials in acute, unipolar, major...
Rosen CJ, Khosla S: Placebo-controlled trials in osteoporosis--proceeding with caution. N Engl J Med 2010, 363: 1365–1367... N Fost - 《Journal of Bone & Mineral Research》 被引量: 32发表: 2010年 Placebo-Controlled Fracture Trials in Osteoporosis — Comment on the Article by Rosen and...
Placebo-Controlled Trials in Type 2 Diabetes. Comments on ethical debates about the use of placebo control trials for type 2 diabetes drugs. Conditions that may warrant the use of placebos; Concerns w... Misbin,Robert,I. - 《Diabetes Care》...
Double-blind randomized placebo-controlled trials, in which a new approval-seeking drug is compared to placebo, are generally considered to be the gold sta... E.,Severus,E.,... - 《Current Treatment Options in Psychiatry》 被引量: 0发表: 2015年 Risk of death with atypical antipsychotic dru...
A temperate phage was induced from exponential phase cells of Erwinia herbicola Y46 by treatment with mitomycin C. The phage was purified by single plaque isolation, and produced in bulk by successive cultivation in young cultures of E. herbicola Y 178. Phages were concentrated from culture filt...
There were more serious adverse events with obeticholic acid. (Funded by Intercept Pharmaceuticals;POISE ClinicalTrials.gov number, NCT01473524;Current Controlled Trials number, ISRCTN89514817.) 展开 DOI: 10.1056/NEJMoa1509840 被引量: 144 年份: 2016 ...
Twenty-five randomized, placebo-controlled trials were included in this review. There were 18 trials that used a sham manual SMT procedure for their placebo control intervention; the most common approach was with an SMT setup but without the application of any thrust. One small pilot study used...
This meta-analysis aimed to determine whether ambulatory blood pressure monitoring (ABPM) results from double-blind, placebo-controlled (DBPC) and prospective, randomized, open-label, blinded-endpoint (PROBE) hypertension trials are statistically comparable.Two DBPC and three PROBE parallel-group studies...
Influence of Sibutramine on blood pressure: evidence from placebo-controlled trials OBJECTIVE:: Sibutramine, a serotonin and norepinephrine transporter inhibitor, is widely used as an adjunctive obesity treatment. There have been concerns ... J Jordan,J Scholze,B Matiba,... - 《International Journal...