PKM2-IN-3 | MedChemExpress 英文名称: 总访问: 68 国产/进口: 进口 半年访问: 9 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 电询 最后更新: 2025-2-13 货号: HY-139667 CAS 号: 2408841-19-8 参考报价: 电询 立即询价 电话咨询 ...
货号: 3855221 品牌:Macklin/麦克林 规格: 5mg 包装: 5mg/瓶 编码: P933982-5mg CAS 编码: 2408841-19-8 价格:¥5,000.00/ 瓶 数量 - + 瓶 保障正品保障增票服务 * 本链接展示、销售的所有产品均不得用于人类或者动物临床诊断或治疗,仅用于工业或者科研等非医疗目的 ...
The levels of PKM2 and IL-1β were high in patients with anti-signal recognition particle autoantibody expression. These proteins might be used as new biomarkers for muscle damage. 展开 关键词: DM PM glycolysis PKM2 NLRP3 inflammasome pyroptosis ...
In vitro studies on the THP-1 cells were also performed. RESULTS :The DM-STEMI group had a higher value of peak TnI and a higher GRACE risk score than the non-DM-STEMI group (p<.05). The highest expression levels of PKM2, NLRP3, interleukin (IL)-1尾, and IL-18 and the lowest ...
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PKM2NLRP3 inflammasomepyroptosisObjectives. Muscle cell necrosis is the most common pathological manifestation of idiopathic inflammatory myopathies. Evidence suggests that glycolysis might participate in it. However, the mechanism is unclear. This study aimed to determine the role of glycolysis in the ...
Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.SALITURO Francesco G.SAUNDERS Jeffrey O....
2-Demethoxy-2,3-ethylenediamino hypocrellin B (EDAHB)A549 cellsPyruvate kinase M2 (PKM2)Proteome2-Demethoxy-2,3-ethylenediamino hypocrellin B (EDAHB) is an efficient photosensitizer that mediates cancer cell apoptosis. In order to better understand the molecular mechanisms involved in its anti...
GPR3 activation induces a rapid increase in glycolysis via formation of complexes between 尾-arrestin2 and key glycolytic enzymes as well as sustained increase in glycolysis through transcription of glycolytic genes. In mice, GPR3 activation in Kupffer cells results in enhanced glycolysis, reduced ...