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Otto Warburg: The journey towards the seminal discovery of tumor cell bioenergetic reprogramming [J]. Biochim Biophys Acta Mol Basis Dis, 2021, 1867(1): 165965. [3] Dayton T L, Jacks T, Vander Heiden M G. PKM2, cancer metabolism, and the road ahead [J]. EMBO Rep, 2016, 17(12):...
In summary, we reveal a molecular link between cell survival regulators and key enzymes of cancer metabolism and our study will provide potential therapeutic significance for HCC patients. Results TSP50 is highly expressed in HCC and survival-associated We evaluated TSP50 transcription levels via ...
Rocking cell metabolism: Revised functions of the key glycolytic regulator PKM2 in cancer. Trends Biochem. Sci. 2012, 37, 309-316. [CrossRef] [PubMed]Chaneton B & Gottlieb E (2012) Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer. Trends Biochem Sci...
PKM2, cancer metabolism, and the road ahead. EMBO Rep. 2016;17(12):1721–30. 20. Zahra K, Dey T, Ashish, Mishra SP, Pandey U. Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis. Front Oncol. 2020;10:159. 21. Lang L, Loveless R, Dou J, Lam T, Chen ...
PKM2, cancer metabolism, and the road ahead. EMBO Rep. 2016;17(12):1721–30. 8. Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, et al. PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in...
PKM2, cancer metabolism, and the road ahead EMBO Rep., 17 (12) (2016), pp. 1721-1730 CrossrefView in ScopusGoogle Scholar [41] J. Xu, C. Jiang, X. Wang, M. Geng, Y. Peng, Y. Guo, S. Wang, X. Li, P. Tao, F. Zhang, Y. Han, Q. Ning, W. Zhu, L. Meng, S. Lu...
Activators of PKM2 in cancer metabolism[J ]. Future Med Chem, 2014,6 ( 10 ) : 1167- 1178.Warner SL, Carpenter KJ and Bearss DJ: Activators of PKM2 in cancer metabolism. Future Med Chem 6: 1167‑1178, 2014.Warner SL, Carpenter KJ and Bearss DJ: Activators of PKM2 in ...
Cancer Metabolism Cutting off the fuel supply to calcium pumps in pancreatic cancer cells: role of pyruvate kinase-M2 (PKM2) Andrew D. James, Daniel A. Richardson, In-Whan Oh, Pishyaporn Sritangos, Thomas Attard, Lisa Barrett & Jason I. E. Bruce British Journal of Cancer volume...
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