pH and pKa are two important values used when talking about acid-base chemistry and it can be hard to distinguish the two. pH is the negative log of the concentration of hydrogen ions in a solution, pH=−log[H+]. The pH of a system is a value that is measured and can change depe...
(acid) in relation to the molecule concentration in the solution. hence, ka represents the strength of an acid and as this value can be in the form of 10-3 to 10-6, the addition of a negative base logarithm allows for this value to be more intuitive. 1 in drugbank, it is possible...
The pKa value is used to indicate the strength of an acid. A lower pKa value indi- cates a stronger acid, indicating the acid more fully disso- ciates in water. Molecules with multiple ionizable centers have multiple pKa values, and knowledge of the pKa of each of the ionizable moieties...
Rank from best acid (low pKa) to worse acid (high pKa). Acid: Acids are the substance that can provideH+ions or receive an electron pair. The reactivity of the conjugate base shares an inverse relation with acid's strength. Lower the reactivity of the conjugate base higher is the acidic...
Gilli P, Pretto L, Bertolasi V, Gilli G (2008) Predicting hydrogen-bond strengths from acid–base molecular properties. The pKa slide rule: toward the solution of a long-lasting problem. Acc Chem Res 42(1):33–44. : 10.1021/ar800001k...
The differences may be explained by different temperature, ionic strength and analytical methods used. The accuracy of the method employed in this work was checked by phosphoric acid titrations. As mentioned before, a ±0.2 pKa value deviation may be expected in our results. Table 2. Macroscopic...
Explore the concepts of pKa and pH values and how they relate to acids and bases. Learn the trends in pKa value for functional groups, acids, and...
The amount of decalcification by the carboxylic acid in the NM omega A on the hydroxyapatite or dentin was strongly dependent on the pKa value of the carboxylic acid in the NM omega A. However, the bond strengths to both the enamel and dentin were not influenced by the amount of ...
The study revealed that the E°' value of the protein is regulated by two molecular mechanisms operating independently of each other. One is based on the Fe-Met coordination bond strength in the protein, which is determined by the amino acid side chain packing in the protein, and the other...