J Mohanty,AC Bhasikuttan,WM Nau,H Pal.Host–guest complexation of neutral red with macrocyclic host molecules: contrasting pK(a) shifts and binding affinities for cucurbit 7 uril and beta-cyclodextrin.The Journal of Physical Chemistry. B. 2006...
Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis. Proc Natl Acad Sci USA. 2020;117:31189–97. Article CAS PubMed PubMed Central Google Scholar Wadhwa R, Colgin L, Yaguchi T, Taira K, Reddel RR, Kaul SC. Rhodacyanine dye MKT-077 inhibits...
However, this calculation assumes that only the neutral species are distributed in the organic phase, disregarding the fact that octanol can dissolve a significant amount of water, allowing the ionic species to partition into octanol through water. This presence of both charged and uncharged species...
A Box plot depicting tumor purity of Luminal A ILC and Luminal A NST based on gene expression data from SCAN-B estimated by package ESTIMATE. B Volcano plot for differential gene expression between Luminal A ILC and Luminal A NST in SCAN-B using DESeq2; red = genes with log(FC)...
This construct takes advantage of the different pH sensitivities of GFP and mCherry (Fig. 1C). Being acid labile (pKa of 6.0 [44]), GFP is inert in acid environments and thus labels efficiently only neutral vesicles (autophagosomes), while mCherry is pH-stable (pKa 4.5 [45]) and can...
Figure 7. Bond critical points (red), ring critical points (yellow) and bond paths illustrated for the anion 8, generated by AIM2000. Conclusion The effects of proximal aromatic residues on anions have been described in the literature extensively in the context of binding studies. We have exami...
Figure 3. Effect of pH on the 19F signal of 4F3HB in the presence of WT 3HB6H at 4 °C. A, 19F signal of 4F3HB bound to 3HB6H at pH 6.5 (orange spectrum) and pH 9.0 (light blue spectrum), and the simulations of the NMR lines are shown in red and blue lines for the pH...
case of kyawthuite, scientists concluded during their study that the gem primarily contains bismuth (a silvery pinkish metal), antimony (a silvery bluish white metal or metalloid), and tetraoxygen (a stable red solid of oxygen molecules), as well as trace amounts of other chemicals and ...
red nodule/macule, or as longitudinal erythronychia. Diagnosis frequently calls for an excisional biopsy, with histopathology notable for a proliferation of several dense- and thin-walled vascular structures lined by a flattened endothelium. Our instance emphasizes the need to give consideration to ...
c, Representative images of co-expression of PKI (red) and the PKA sensor tAKARα (green) in the same cells (top), and representative traces of enforced running-induced PKA activity in neurons of the mouse motor cortex without (bottom left) and with (bottom right) PKI expression. n (FOV...