Studies of Piperazine-Based Polymers and Hydrogels. Ph.D. dissertation, Nanyang Technological University, Singapore, 2000.Roshan Deen, G.; Gan, L.H. Influence of amino group pKa on the properties of stimuli-responsive piperazine-based polymers and hydrogels. J. Appl. Polymer Sci. 2008, 107, ...
N-terminal amino group of ubiquitin by NMR received: 14 November 2016 accepted: 26 January 2017 Published: 02 March 2017 Alain Oregioni1,*, Benjamin Stieglitz2,†,*, Geoffrey Kelly1, Katrin Rittinger2 & Tom Frenkiel1 Ubiquitination regulates nearly every aspect of cellular life....
Define PKA. PKA synonyms, PKA pronunciation, PKA translation, English dictionary definition of PKA. n. Any of a group of kinases that phosphorylate the amino acids serine, threonine, and tyrosine in certain proteins, that regulate essential aspects of ce
Hi,I had this question when I had to solve a problem where one point was which is more basic carboxylate anion or amino group. The pKa-s are 36 for amino and 3.7 for HCOOH, but one of the value is for NH3 and other for HCOOH, how to i get for HCOO- Logged Schrödinger...
Influence of amino group pKa on the properties of stimuli‐responsive piperazine‐based polymers and hydrogels Linear homopolymers of N -acryloyl- N -alkyl piperazine ( N -alkyl: methyl, ethyl, or propyl) and their corresponding crosslinked hydrogels were prepared. ... GR Deen,LH Gan - 《Journ...
By rational derivatization of 5-isoquinoline sulfonamides, it was found that the introduction of a methyl group to the sulphonamidic nitrogen on the known PKA inhibitors N-(2-aminoethyl)isoquinoline-5-sulfonamide (H-9, 1) and N-(2-(4-bromocinnamylamino)ethyl)isoquinoline-5-sulfonamide (H-89...
As applications, we have derived the p K a value of the side chain of an amino acid and almost reproduced the experimental value. By using our computing schemes, we showed the influence of hydrogen bonds on the p K a values in the case of tripeptides, which decreases the p K a value...
Amino Acids, Peptides, and Proteins Robert J.Ouellette,J. DavidRawn, inPrinciples of Organic Chemistry, 2015 Titration of Amino Acids The pKavalues of thecarboxyl groupand the ammonium group of an amino acid, as well as the pHi, can be determined by titrating the conjugate acid withbase.Fig...
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(n = 20–24 cells per group).eRepresentative confocal images of cultured adult cardiomyocyte infected with wild type or R601F HDAC4-GFP, paced at 1.5 Hz for 0, 15 or 30 min.fAverage values of HDAC4 FNuc/FCytoratio in cells overexpressing wild type or R601F HDAC4-GFP with or ...