Whole slide imagingis a method principally employed when scientists need to image a large, relatively two-dimensional sample that expands beyond a single microscope field of view. Typical applications include imaging of histological tissues that have been cut into thin slices and placed on a glass s...
Rich Cifelli took me under his wing and showed me the ropes. I started going out on digs, learned the basics of curatorial work, how to mold and cast fossils, how to screenwash matrix and then pick microfossils out of the concentrate under a dissecting microscope, and—perhaps most ...
One of the best pieces of advice I ever got was from Nick Czaplewski, who was a curator at OMNH when I was starting out and for many years thereafter. He told me that you end up writing papers not only to your colleagues but also to your future self, because there’s no way you...
The cryo-electron microscope structure of Rag A/C bound to mTORC1 shows the details of Rag A/C binding to the Raptor subunit of mTORC1. The binding of Rag heterodimer does not change the conformation of mTORC1, but activates it by targeting mTORC1 to the lysosome, which is contrary to ...