Iron (Fe) is an essential element, but Fe metabolism is poorly described in fish and the role of ferrireductase and transferrin in iron regulation by teleosts is unknown. The aim of the present study was to provide an overview of the strategy for Fe handling in rainbow trout, Oncorhynchus ...
► PTOX is a non-heme, di-iron carboxylate protein localized to thylakoid membranes that displays sequence similarity to the mitochondrial alternative ox... AE Mcdonald,AG Ivanov,R Bode,... - BBA - Bioenergetics 被引量: 245发表: 2011年 The physiological role of endoglin in the cardiovascula...
Iron- and sulfate-reducing microorganisms play an important role for alkalinity-generating processes in mining lakes with low pH. In the acidic mining lake 111 in Lusatia, Germany, a passive in situ remediation method was tested in a large scale experiment, in which microbial iron and sulfate re...
摘要: Multiple physiological roles of ovotransferrin are reviewed. Ovotransferrin plays a major role in avian natural immunity. Experimental evidences support that the ovotransferrin is a multi-functional protein. New biotechnolgical applications of ovotransferrin could be envisaged....
We describe the well-known interactions with RNA polymerase as well as a broader range of cellular target pathways controlled by (pp)pGpp, including DNA replication, transcription, nucleotide synthesis, ribosome biogenesis and function, as well as lipid metabolism. Finally, we review the role of ...
These results suggest a possible role for the ferritin-iron saturation in the assessment of iron stores in patients suffering from acute phase response. In addition, the considerable amount of iron in ferritin suggests the need to revise the physiological role of this substance in relation to the...
Zinc is a trace mineral which is vital for the functioning of numerous cellular processes, is critical for growth, and may play an important role in cancer... BJ Grattan,HC Freake - 《Nutrients》 被引量: 61发表: 2012年 Free radicals and mitochondrial dysfunction in Parkinson's disease. The...
The clinical manifestations of cerebral malaria (CM) are well correlated with underlying major pathophysiological events occurring during an acute malaria ... PN Mimche,TL Vivas - 《Malaria Journal》 被引量: 97发表: 2011年 The Role of Iron Toxicity in Oxidative Stress-induced Cellular Degeneration...
Ferritin is a ubiquitous intracellular iron storage protein that plays a crucial role in iron homeostasis. Animal tissue ferritins consist of multiple isoforms (or isoferritins) with different proportions of H and L subunits that contribute to their structural and compositional heterogeneity, and thus...
This chapter reviews the enzymatic pathways, the structure-function relationships, and the role of CYP24A1 in the catabolism of 1,25(OH)2D. Catabolism of 1,25(OH)2D occurs through CYP24A1-mediated modification of the secosteroid's aliphatic side-chain. CYP24A1 is a mitochondrial inner membra...