Iron-sulfur clusters - reactivities - functions - cluster interconversions - metalloenzymesIron-sulfur clusters are prevalent in biological systems. Through studies of iron-sulfur proteins and synthetic model clusters, it was realized early on that these clusters functioned as facile electron transfer ...
Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing Rahul Singh, Yuan Wu, Alba Herrero del Valle, Kendra E. Leigh, ... Yorgo ModisMarch 2024 Article 105711 View PDF Article preview select article HDAC6/aggresome processing pathway importance for inflammasome formation ...
It functions as a protein cofactor in fundamental pathways including respiration, photosynthesis and the biogeochemical cycling of sulfur and nitrogen. There are two major types of iron-containing protein cofactors, haemes and iron–sulfur clusters. The most common iron–sulfur cluster is the cubane-...
6,7,8,9,10,11,12,13,14,15,16,17]. Interestingly, nature responded to this issue in an unforeseen fashion. Recalling the findings of Lovely et al. on iron nanoparticles (magnetite) synthesis by bacteria, the exploration of nature’s ability to reduce metal cations to...
The pluripotent gaseous messenger molecule nitric oxide (NO) controls vital functions such as neurotransmission or vascular tone (via activation of soluble guanylyl cyclase), gene transcription, mRNA translation (via iron-responsive elements), and post-translational modifications of proteins (via ADP-ribos...
(+)-Nicotianamine and its naturally occurring antipode exhibited the same biological activity with regard to chlorophyll formation of chlorotic leaflets of the mutant chloronerva. It is therefore concluded that nicotianamine does not exert its functions by a stereospecific binding to a macromolecular surf...
this review provides an overview of what is currently known regarding underlying mechanisms of action by which diet may influence mental and brain health. The mechanisms of action associating diet with health outcomes are complex, multifaceted, interacting, and not restricted to any one biological path...
TETs functions and binding partners The primary functions of TETs are able to oxidate 5mC, and the products are subsequently involved in DNA demethylation.64,65,66Besides, TET genes expression in different tissues are analyzed using the proteinatlas database67(https://www.proteinatlas.org/) in ...
Hydrogen sulfide (H2S) is proposed to be an endogenously synthesized small-molecule signaling agent involved in a variety of physiological functions.Many of the biological actions proposed for H2S may be due to the presence of other sulfur species such as per- and/or polysulfides.Persulfides (RSS...
Lovallo provides an introduction to the concept of psychological stress, its physiological manifestations, and its effects on health and disease. The book concentrates on the psychophysiological relationship between cognitions, emotions, brain functions, and the peripheral mechanisms by which the body is ...