The subtype of transthyretin (TTR) protein mutation, its tissue distribution, and the amount of amyloid deposition largely determine the clinical manifestations of TTR-related amyloidosis (ATTR). The key characteristic of ATTR that should raise clinical suspicion for this disorder remains the reliable ...
Department of Internal Medicine, AP-HP, Tenon Hospital, Paris, France Inès Elhani & Sophie Georgin-Lavialle National French Reference Centre for Auto-inflammatory Diseases and Inflammatory Amyloidosis (CEREMAIA), Paris, France Inès Elhani, Pascal Heydacker, Anne-Sophie Tavernier, Sophie Georgin-La...
This may lead to various diseases, such as amyloidosis. In vitro experiments have demonstrated that QDs coated with a hydrophilic polymer accelerate the formation of fibrils of human β2 microglobulin, which are then arranged into multilayered structures on the particle surface; this results in a ...
Recent experimental evidence indicates that in the cortex, in addition to the silencing of a fraction of neurons, other neurons are hyperactive in... MA Busche,X Chen,HA Henning,... 被引量: 257发表: 2012年 Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel ...
Association of sarcoidosis, monoclonal gammopathy of undetermined significance and cardiac amyloidosis: a case report Laboratory tests showed only mild hypercalcemia. Pulmonary function tests were unremarkable and worsening dyspnea, orthopnea and paroxysmal nocturnal dyspnea ... AF Amaral,MRD Oliveira,FE Arimu...
LVH is a phenotype characterizing several heart diseases and physiological adaptations: HHD, aortic stenosis, Fabry disease, cardiac amyloidosis, hypertrophic cardiomyopathy (HCM), and athlete's heart are the most recurring causes of LVH, sometimes posing challenges for the differential diagnosis [18,19...