Phosphoramidite chemistry is the gold standard method for DNA synthesis that has been used in the industry for almost 35 years. Since its discovery, its simplicity and high efficiency have allowed large volumes of oligonucleotide sequences to be synthesized up to 200 base pairs in length. Currently...
F. Mugnier, C. Meier, Phosphoramidite Chemistry for the Synthesis of cycloSal-Pro- Nucleotides, Nucleosides Nucleotides 1999, 18, 941-942.MUGNIER, FLORENCE ET AL: "Phosphoramidite chemistry for the synthesis of Cyclosal-pro-nucleotides" PROCEEDINGS OF THE XIII INTERNATIONAL ROUND TABLE "NUCLEOSIDES,...
The chemical synthesis of DNA and RNA is universally carried out using nucleoside phosphoramidites or H-phosphonates as synthons. This review focuses on the phosphorus chemistry behind these synthons and how it has been developed to generate procedures whereby yields per condensation approach 100% wi...
In addition to our Thermo Scientific phosphoramidites, we offer custom services for oligonucleotide chemistry tailored to fit your needs in diagnostic and therapeutic applications. We are fully set up to provide customization of our existing phosphoramidites, synthesis of new compounds, and development ...
We describe the synthesis of protected phosphoramidites of deoxyriboguanosine and guanosine derivatives containing a thiopropyl tether at the guanine N2 (7a,b) for site-specific crosslinking from the minor groove of either DNA or RNA to a thiol of a protein or another nucleic acid. The thiol ...
Novel post DNA synthesis chemistry for preparing oligonucleotides containing O6-modified purines O6-Alkylguanine DNA alkyltransferase (AGT) is a key target for inhibition during cancer chemotherapy. A large number of O6-modified-guanine analogues have been developed as AGT inhibitors, of which benzyl ...
The chemical synthesis of DNA and RNA is universally carried out using nucleoside phosphoramidites or H-phosphonates as synthons. This review focuses on the phosphorus chemistry behind these synthons and how it has been developed to generate procedures whereby yields per condensation approach 100% ...
Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry. DMS(O)MT aminolink C6 DMS(O)MT aminolink C6 An amidite for the introduction of amino group. FAM 亚磷酰胺,6-异构体 FAM Phosphoramidite, 6-Isomer Single isomer 6-FAM phosphoramidite for the synthesis of modifi...
To help drug developers obtain materials that are not available off the shelf, we offer world-class capabilities and custom chemistry to develop and manufacture molecules for oligo therapeutics. Find out more › 浏览此商品的顾客同时也查看了 Bz-dA Phosphoramidite, standard grade, serum vial bottle...
storedbelow-20°Cforseveralmonths. 运输条件:Evaluationsamplesolution:shipwithblueice Allotheravailablesize:shipwithRT,orblueiceuponrequest 生物活性 靶点:DNA 信号通路:DNASynthesis 产品描述: Phosphoramiditeforthesynthesisofoligonucleotideswith5'-terminalalkyneforClickChemistry. ...