Nucleosides and NucleotidesF. Mugnier, C. Meier, Phosphoramidite Chemistry for the Synthesis of cycloSal-Pro- Nucleotides, Nucleosides Nucleotides 1999, 18, 941-942.MUGNIER, FLORENCE ET AL: "Phosphoramidite chemistry for the synthesis of Cyclosal-pro-nucleotides" PROCEEDINGS OF THE XIII INTERNATIONAL ...
Phosphoramidite chemistry is the gold standard method for DNA synthesis that has been used in the industry for almost 35 years. Since its discovery, its simplicity and high efficiency have allowed large volumes of oligonucleotide sequences to be synthesized up to 200 base pairs in length. Currently...
The chemical synthesis of DNA and RNA is universally carried out using nucleoside phosphoramidites or H-phosphonates as synthons. This review focuses on the phosphorus chemistry behind these synthons and how it has been developed to generate procedures whereby yields per condensation approach 100% wi...
In addition to ourThermo Scientific phosphoramidites, we offer custom services for oligonucleotide chemistry tailored to fit your needs in diagnostic and therapeutic applications. We are fully set up to provide customization of our existing phosphoramidites, synthesis of new compou...
We describe the synthesis of protected phosphoramidites of deoxyriboguanosine and guanosine derivatives containing a thiopropyl tether at the guanine N2 (7a,b) for site-specific crosslinking from the minor groove of either DNA or RNA to a thiol of a protein or another nucleic acid. The thiol ...
SYNTHESIS OF MONO- AND DIMANNOSIDE PHOSPHORAMIDITE DERIVATIVES FOR SOLID-PHASE CONJUGATION TO OLIGONUCLEOTIDES[J].Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry 1995,40(40).Akhtar, S., Routledge, A., Patel, R., and Gardiner...
A new class of phosphanylmethylphosphonate reagents has been developed to enable the controlled synthesis of methylene bisphosphonate mono- and diesters. Condensation of such reagents with an alcohol of choice through azole-mediated phosphoramidite chemistry followed by in鈥卻itu oxidation provides ...
Current Protocols in Nucleic Acid Chemistry The phosphoramidite approach has had a major impact on the synthesis of oligonucleotides. This unit describes parameters that affect the performance of thi... SL Beaucage,MH Caruthers - Current protocols in nucleic acid chemistry / edited by Serge L. Beauc...
This review reports on the synthesis of 7-deazapurine 2'-deoxyribonucleosides, including -D- and -Lenantiomers, fluoro derivatives, and 2',3'-dideoxyribonu... S Budow,X Peng,F Seela - 《Current Organic Chemistry》 被引量: 63发表: 2008年 ...
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