Nicolau J, Souza DN, Nunez-Burgos G (2000) Regulation of phosphofructokinase-1 on submandibular salivary glands of rats after iso- proterenol administration. Arch Physiol Biochem 108(5):437-443Nicolau J, Souza DN, Nunez-Burgos G. Regulation of phosphofructokinase-1 on submandibular salivary ...
Phosphofructokinase 1 (PFK1) plays a critical role in glycolysis; however, its role and regulation in tumorigenesis are not well understood. Here, we demonstrate that PFK1 platelet isoform (PFKP) is the predominant PFK1 isoform in human glioblastoma cells and its expression correlates with total P...
With altered glycolytic flux being a hallmark of cancers6, these new structures allow a molecular understanding of the functional consequences of somatic PFK1 mutations identified in human cancers. We characterized three of these mutations and show they have distinct effects on allosteric regulation of...
I. BrandSpringer Berlin HeidelbergSoling, H. D. and Brand, I. (198 1) Regulation of phos- phofructokinase by phosphorylation-dephosphorylation - state of the Art in: Metabolic Interconversion of Enzymes, (Holzer, H. ed) Springer-Verlag, Berlin, (in press)....
J. (1990) Regulation of phosphofructokinase at physiological con- centration of enzyme studied by stopped-flow measure- ments. Biochim. Biophys. Res. Commun. 167, 1214-1220.BARJ, ., MARTINEZ-COS0TA.H, . & ARAGONJ,. J. (1990).Regulation of phosphofructokinase at physiological concentration of...
17.Regulation of Carbohydrate Metabolic Enzymes by Protein Reversible Phosphorylation in Apple Fruit;苹果果实中糖代谢酶的可逆磷酸化修饰及其活性调控 18.Purification of Phosphorylase and Enzymatic Sythesis of Glucose-1-phosphate;磷酸化酶的分离及葡萄糖-1-磷酸的酶法合成 ...
Phosphofructokinases (PFK; EC 2.7.1.11) are tetrameric enzymes that have a key role in the regulation of glycolysis; as such, they are subject to allosteri... RA Poorman,A Randolph,RG Kemp,... - 《Nature》 被引量: 384发表: 1984年 Pyrophosphate-dependent phosphofructokinase, an anaerobic ...
Eukaryotic ATP-dependent 6-phosphofructokinases (Pfks) differ from their bacterial counterparts in a much more complex structural organization and allosteric regulation. Pichia pastoris Pfk (PpPfk) is, with ∼ 1 MDa, the most complex and probably largest eukaryotic Pfk. We have determined the crys...
It is unknown whether JNK1 regulates glycolysis, an important metabolic process that is involved in cell survival, and if so, whether the regulation depends on Thr-201 phosphorylation of Bad. Here we report that phosphorylation of Bad by JNK1 is required for glycolysis through activation of ...
Article: Allosteric regulation of phosphofructokinase controls the emergence of glycolytic oscillations in isolated yeast cells