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shown to phosphorylate a number of different cellular proteins, including p53, c-Myc, c-Jun, heat shock factor-1 (HSF-1), and cyclin D1. GSK3 beta also has been shown to phosphorylate aberrant sites on the microtubule associated protein tau, which is critical for the progression of ...
phospho-C-Myc(Thr373) 磷酸化致癌基因C-Myc抗体 Anti-GLIPR1/Biotin 生物素标记的脑胶质瘤发病机制相关蛋白1抗体 Anti-PSMC1/Proteasome 19S S4/RBITC 罗丹明(RBITC)标记的 26S蛋白酶调节亚型抗体 Anti-TNF-alpha/Cy3 Cy3标记的肿瘤坏死因子-α抗体 IFNA11/Limitin/Interferon alpha 11 干扰素α11抗体...
Upon activation, it has been shown to phosphorylate a number of different cellular proteins, including p53, c-Myc, c-Jun, heat shock factor-1 (HSF-1), and cyclin D1. GSK3 beta also has been shown to phosphorylate aberrant sites on the microtubule associated protein tau, which is critical...
NAMPT activity increases the abundance of NAD+, also a coenzyme of the deacetylase silent information regulator 1 (SIRT1), thereby activating the oncogene c-myc and inhibiting the senescence and apoptosis responses to oncogenic activation [100]. Moreover, NAMPT is actually transcriptionally acti...
The plasma membrane of polarized hepatocytes is functionally divided into two domains: the apical and basolateral. Our focus is to define the molecular basis of polarized protein sorting of newly-synthesized membrane and secretory proteins in WIF-B cells
In response to membrane attack complexes (MAC), ZFYVE21 is post-translationally stabilized on MAC+Rab5+ endosomes in a Rab5- and PI(3)P-dependent manner. ZFYVE21 promotes SMURF2-mediated polyubiquitinylation and proteasome-dependent degradation of endosome-associated PTEN to induce vesicular ...
Intramolecular Contact Switch Is Crucial for Brd4-Regulated c-Myc and c-Fos Gene Transcription To define whether the intramolecular contact switch is a general mechanism for Brd4-regulated transcription, we further analyzed Brd4 recruitment to c-Myc and c-Fos genes not containing obvious p53-binding...
Upon activation, it has been shown to phosphorylate a number of different cellular proteins, including p53, c-Myc, c-Jun, heat shock factor-1 (HSF-1), and cyclin D1. GSK3 beta also has been shown to phosphorylate aberrant sites on the microtubule associated protein...
Upon activation, it has been shown to phosphorylate a number of different cellular proteins, including p53, c-Myc, c-Jun, heat shock factor-1 (HSF-1), and cyclin D1. GSK3 beta also has been shown to phosphorylate aberrant sites on the microtubule a...