Sperow M et al (2012) Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration. J Physiol 590(Pt 4):777–792 CentralSperow M, Berry RB, Bayazitov IT, Zhu G, Baker SJ, Zakharenko SS (2011) Phosphatase and tensin...
1.Phosphatase and tensin homologue deleted on chromosome 10, pten.人第10号染色体缺失的磷酸酶及张力蛋白同源的基因
目的研究子宫内膜腺癌组织中第10号染色体缺失的磷酸酶和张力蛋白同源物基因(PTEN)和血管内皮生长因子VEGF的表达与子宫内膜腺癌血管生成的关系。6) phosphatase and tensin homologue deleted on chromosome ten 第10染色体缺失与张力蛋白同源的磷酸酶基因 1. Objective:To evaluate the relationship and expression of phos...
aThe PTEN (phosphatase and tensin homologue deleted on chromosome ten) tumor suppressor gene modulates cell growth and survival through mechanisms that are incompletely understood PTEN (在染色体删除的磷酸酶和tensin同源染色体十)肿瘤遏抑器基因通过残缺不全地被了解的机制调整细胞成长和生存 [translate] ...
Phosphatase and Tensin Homologue Phosphatase and tensin homologue (PTEN), encoded by a gene located at chromosome 10q23, functions as a tumor suppressor by counteracting the activity of PI3K. PTEN has many substrates, but its most important reaction is the dephosphorylation of PIP3 to PIP2. Abse...
PTEN A gene on chromosome 10q23.3 which encodes PTEN (phosphatase and tensin homolog), a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase protein, which acts as a tumour suppressor by negatively regulating the AKT/PKB-signalling pathway. ...
Stimulation of PI3K promotes phosphorylation of Akt resulting in follicle survival and activation of growth whereas this pathway is suppressed by the actions of the phosphatase and tensin homologue (PTEN). The aim of this study was to determine the effect of dipotassium bisperoxo(5-hydroxypyridine-2...
Phosphatase PTEN in neuronal injury and brain disorders The phosphatase and tensin homologue PTEN was originally identified as a tumor suppressor. In the CNS, mutation or inactivation of PTEN is best known for p... C Ning,YH El-Hayek,E Gomez,... - 《Trends in Neurosciences》 被引量: 160...
Stimulation of PI3K promotes phosphorylation of Akt resulting in follicle survival and activation of growth whereas this pathway is suppressed by the actions of the phosphatase and tensin homologue (PTEN). The aim of this study was to determine the effect of dipotassium bisperoxo(5-hydroxypyridine-2...
Inhibition of Phosphatase and Tensin Homologue (PTEN) in Human Ovary In Vitro Results in Increased Activation of Primordial Follicles But Compromises Devel... Inhibition of phosphatase and tensin homologue (PTEN) in human ovary in vitro results in increased activation of primordial follicles but ...