Phenyl-N-tert-butylnitrone demonstrates broad-spectrum inhibition of apoptosis-associated gene expression in endotoxin-treated rats. Arch Biochem Biophys 1999; 365(1): 71–4Stewart CA, Hyam K, Wallis G, Sang H, Robinson KA, Floyd RA, et al. Phenyl-N-tert- butylnitrone demonstrates broad-...
别名N-叔丁基苯硝酮 英文别名PBN | Phenyl-N-tert-butylnitrone | F0001-0991 | 2-Propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide, (N(Z))- | N-tert-Butyl-.alpha.-phenylnitrone | (Z)-N-Benzylidene-2-methylpropan-2-amine oxide | n-tert-butyl phenyl nitrone | (Z)-benzylidene(ter...
网络硝酮 网络释义 1. 硝酮 更有效的抗氧化剂α 苯基叔丁基硝酮(α -phenyl-N-tertburyl nitrone)能阻断细胞内氧自由基生成,现已开始临床试验,今后有 … www.docin.com|基于 1 个网页
Effects of alpha-phenyl-N-tert-butyl nitrone (PBN) on compression injury of rat spinal cord. Free Radical Res 1997; 27: 187-196.Li, G.L., Forooque, M., Holtz, A., Olsson, Y., 1997. Effects of a-phenyl-N-tertbutyl nitrone (PBN) on compression injury of rat spinal cord. Free ...
Phenyl N-tert-butylnitrone (PBN) is the parent of a family of nitrones used as spin-trapping agents to trap free radicals. PBN's pharmacological effects in animal models are extensive, ranging from protection against death after endotoxin shock, protection from ischemia-reperfusion injury, to inc...
beta-amyloidcytotoxicityphenyl N-tert-butyl nitronevasoactivityIn recent years evidence has increased that vascular disease is associated with cognitive impairment... MMB Breteler,A Ott,A Hofman - Springer Berlin Heidelberg 被引量: 8发表: 1999年 加载更多来源...
PP46 Phenyl n-tert-butylnitrone (PBN), a non-toxic trap of free radicals, inhibits pro-inflammatory cytokinemediated activation of JNK/SAPK and apoptosis in human osteoarthritis chondrocytes Author links open overlay panelShow more Add to Mendeley Share Cite https://doi.org/10.1016/S1063-4584(...
The spin trapping agent phenyl-N-tert-butylnitrone (PBN) was used in vivo to directly assess the formation of ROS during DFP (1.75 mg/kg, s.c.) induced muscle hyperactivity. Pretreatment with PBN (300 mg/kg, i.p.), the concentration necessary for in vivo spin trapping, prevented muscle...
electron impact MSC-phenyl N-tert-butyl nitronePBNN-tert-butyl C-phenyl nitroneThe electron impact mass spectra of fifteen 4-substituted PBN's and PBN itself have been obtained using the probe method. Strong molecular ion peaks were observed in most cases. Fragmentation follows two major ...
alpha-Phenyl-tert-N-butyl nitrone (PBN), a potent reactive oxygen species (ROS) scavenger, has shown robust neuroprotective properties in several models of acute brain injury, although not previously evaluated in traumatic brain injury (TBI). In this study, we assessed the potential efficacy of ...