While Ph and phenyl uniquely denoteC6H5, substituted derivatives are often using phenyl terminologies.O2NC6H4, for example, is nitrophenyl andF5C6is pentafluorophenyl. The monosubstituted phenyl groups (i.e., disubstituted benzenes) are associated with electrophilic aromatic substitution reactions, and ...
In one aspect, the invention relates to substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical composition...