Define phase II. phase II synonyms, phase II pronunciation, phase II translation, English dictionary definition of phase II. Noun 1. phase II - a clinical trial on more persons than in phase I; intended to evaluate the efficacy of a treatment for the con
Define Phase II trials. Phase II trials synonyms, Phase II trials pronunciation, Phase II trials translation, English dictionary definition of Phase II trials. Noun 1. clinical trial - a rigorously controlled test of a new drug or a new invasive medical
ClinicalTrials.gov identifier: NCT01593995.doi:10.1007/s00520-015-2783-9In Gyu HwangJung Hun KangSung Yong OhSuee LeeHyo-Jin KimSpringer Berlin HeidelbergSupportive Care in CancerIn GyuHwang, Jung HunKang, Sung YongOh, SueeLee, Sung-HyunKim, Ki-HoonSong, ChoonheeSon, Min JaePark, Myung ...
Phase 1 Clinical Trialmeans a Clinical Trial of a Product on sufficient numbers of normal volunteers and/or patients that is designed to establish that such Product is safe for its intended use and to support its continued testing in Phase 2 Clinical Trials. For purposes of this Agreement, ‘...
This is not surprising as 2ME2 is not expected to directly influence the transcription of either of these genes (14), and changes in bFGF and VEGF are more likely to be markers of disease regression or progression. As clinical activity of 2ME2 in this study was modest, and the majority ...
that ‘zero mutation ctDNA’ status is the main predictive factor for anti-EGFR rechallenge efficacy. Overall, these observations suggest that a predefined time limit11might be ineffectual for a clinical selection of cases to be rechallenged, whereas ctDNA measurement enables definition of potentially...
Vismodegib at the dose of 150 daily is the recommended Phase 2 dose based on Phase 1 clinical trials.20 Treatment was continued until evidence of disease progression or unacceptable toxicities. All imaging studies and responses were assessed independently by certified radiologists using RECIST criteria ...
There are several ongoing randomized and non-randomized prospective clinical trials, a recent systematic search of clinicaltrials.gov revealed 16 ongoing or planned trials with a total planned participant count of 615 [20]. However, all of these reported a planned maximal radiation dose of 25 Gy...
Objective To determine 2-year overall survival (OS) using perioperative chemotherapy for resectable PDA. Design, Setting, and Participants This was a randomized phase 2 trial of perioperative chemotherapy with a pick-the-winner design. It was conducted across the National Clinical Trials Network, incl...
Based on the importance of risk factors, the logical next steps would be to: 1) analyze more specifically the process of new lesion declaration and to 2) improve tumor burden assessment. Future clinical trials will certainly benefit from new technologies in reducing human interactions and involving...