Background/aims: Healthy volunteers in phase 1 clinical trials contribute to the development of safe drugs and other biologics and accept risks and burdens without anticipated health benefits from participation. Although emerging data have shown that healthy volunteers are influenced by risk, some still...
Phase 1 clinical trial in healthy human volunteers to determine the safety, tolerability and pharmacokinetics of GS-5734 Status: Recruiting Phase of Trial: Phase I Latest Information Update: 26 Oct 2015 Price : €40 * Buy Profile Note: Adis is an information provider. Final gross...
1.Phase I Clinical Trial of Recombinant Human Cytotoxic T Lymphocyte Associate Antigen-4 in Healthy Volunteers;注射用重组人CTLA4-抗体融合蛋白Ⅰ期临床试验 2.Evaluation on safety of domestic pandemic influenza vaccine among healthy adults in phase Ⅰ clinical trials国产大流行流感疫苗Ⅰ期临床试验安全性评...
FDA has granted clearance for the commencement of Phase 1 clinical trials of STI-2020 (COVI-AMGTM) in healthy volunteers and COVID-19 patients with mild symptoms. STI-2020, a monoclonal antibody, has been engineered for ultra-high potency, which potentially translates to a small...
Safety and immunogenicity of an optimized self-replicating RNA platform for low dose or single dose vaccine applications: a randomized, open label Phase I study in healthy volunteers Here the authors report an optimized self-replicating RNA (srRNA) vaccine approach that generates protective immunity...
NovelMed Therapeutics, Inc. recently announced topline results from First-in-Human Phase 1 clinical trial of its complement blocker monoclonal anti-Properdin antibody, known as NM3086...
CLINICAL TRIALS AND HEALTHY VOLUNTEERS In March 2006, six men who were taking part in testing a new drug, known as 'TGN1412', suffered multiple organ failure. This was a Phase I non-therapeutic ... Pamela R. Ferguson* - 《Medical Law Review》 被引量: 45发表: 2008年 Designs of drug-...
IMVT-1402 is designed to be a potentially best-in-class anti-FcRn antibody for the treatment of IgG-mediated autoimmune diseases. In the initial results of a Phase 1 clinical trial in healthy volunteers, IMVT-1402 demonstrated favorable pharmacodynamic...
today announced interim data from its ongoing Phase 1 clinical trial of VG-3927 in healthy volunteers. Collectively, the interim safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) profile supports continued clinical development of VG-3927 as a potential once-daily oral therapy for AD...
The study was an open-label, dose-escalation phase 1 clinical trial (RT-CoV-2 study) enrolling healthy volunteers belonging to two cohorts based on age: younger adults (18 to 55 years old) and older adults (65–85 years old). Each cohort consisted of 3 arms of 15 volunteers each (a ...