Data driven evaluation of healthy volunteer characteristics at screening for phase I clinical trials to inform on study design and optimize screening processesALANINE aminotransferaseCLINICAL trialsEXPERIMENTAL designEPIDERMAL growth factor receptorsGLOMERULAR filtration rate...
Abstract CT168: Clinical pharmacology of AZD4635 (A2ARi): Integration of PK data from cancer patients (CP) and healthy volunteer (HV) clinical trials to pr... Abstract CT168: Clinical pharmacology of AZD4635 (A2ARi): Integration of PK data from cancer patients (CP) and healthy volunteer (...
Clinicopathologic correlation In this consecutive series of volunteer subjects, those who were judged clinically to be cognitively healthy (CDR 0) had brains with very few SPs or NFTs, except for 4 subjects with sufficient neocortical SP densities to meet neuropathologic criteria38 for AD, 2 of wh...
Clinical trial 2The effect of a progesterone receptor modulator on breast tissue in women with BRCA1 and 2 mutations, clinicaltrials.gov,NCT01898312; registered on 07 May 2013. Clinical trial 3A pilot prevention study of the effects of the anti- progestin Ulipristal Acetate (UA) on surrogate ma...
Blood pressure changes and chemical constituents of particulate air pollution: results from the healthy volunteer natural relocation (HVNR) study Environ. Health Perspect., 121 (2013), pp. 66-72 CrossrefGoogle Scholar Wu et al., 2010 S. Wu, F. Deng, J. Niu, Q. Huang, Y. Liu, X. Gu...
controlled. The medical authorities become aware of harmful substance or risks associated with the use of some product ONLY after they receive reports about serious side-effects, illnesses caused by these products or even lethal cases. Do you really want to be the healthy volunteer who goes for ...
Exercise, Education, Friends, Volunteer, Stay Calm--the Better Brain Prescription. Must reading if you wonder why some people remain sharper than others as they age. "When the Midus team (a National Institute of Aging mega-research project studying mid-life) put their data together, they not...
Exercise, Education, Friends, Volunteer, Stay Calm--the Better Brain Prescription. Must reading if you wonder why some people remain sharper than others as they age. "When the Midus team (a National Institute of Aging mega-research project studying mid-life) put their data together, they not...
My husband actually is a volunteer firefighter, partially because of [the community paramedic]. And it was just like a picture-perfect moment where [the community paramedic] holding [child’s name] and this onesie and he’s in his paramedic outfit, and I’m like, ‘Awwww!’ (Postpartum...
Here, we report a study aiming to assess whether 'interpersonal values' (conditioning the direct interactions with others) of healthy subjects who volunteer for phase I studies are different from the general population.Methods: The study population consisted of 138 consecutive healthy subjects who ...