Phase 1 clinical trial of intralesional injection of Candida antigen for the treatment of warts. Arch Dermatol. 2010;146:1431–3.Kim KH, Horn TD, Pharis J, et al. Phase 1 clinical trial of intralesional injection of Candida antigen for the treatment of warts. Arch Dermatol 2010; 146 (12...
clinicalphasetrial临床preclinicalbiologics 11Session6–ClinicalTrialAssessmentPhaseIClinicalTrialPresentationtoAPECPreliminaryWorkshoponReviewofDrugDevelopmentinClinicalTrialsCeliaLourenco,PhD,Manager,ClinicalGroupIOfficeofClinicalTrialsTherapeuticProductsDirectorateL1Slide1L1Lourenco;28.01.20082Disclaimer:theinformationwithinthis...
a clinical stage cell therapy company and wholly owned independently operated subsidiary of Bayer AG, announced today details of 18-month data from the phase I clinical trial for bemdaneprocel, an investigational allogeneic stem cell derived cell the...
Here we report our single-institution phase 1 clinical trial aiming to determine the safety of intravenous injection of Seprehvir in children and young adults with non-CNS solid tumors by recording adverse events and any dose-limiting toxicities (DLTs) of intravenous Seprehvir at the doses given...
11 Such broad specificity may potentially have clinical utility; for example, inhibition by ibrutinib of interleukin-2–inducible T-cell kinase in T cells12 has resulted in a clinical trial in T-cell lymphoma (NCT02309580), whereas the inhibition of ErbB kinases may lead to application in solid...
Supplementary Table 1, Supplementary Data and clinical study protocol (redacted). Reporting Summary Source data Source Data Fig. 2 Source data. Source Data Fig. 3 Source data. Source Data Fig. 4 Source data. Source Data Extended Data Fig. 1 Source data. Source Data Extended Data Fig. 2 Sou...
Clinical trial protocol. Supplementary Note 2. Clinical trial STROBE checklist. Supplementary Note 3. Clinical trial statistical analysis plan. Reporting Summary Source data Source Data Fig. 1 Unprocessed western blots (combined file). Rights and permissions Springer Nature or its licensor (e.g. a ...
Clinical trial protocol. Source data Source Data Extended Data Fig. 2 Source data for the screening of individual patient TIL fragments for autologous reactivity by IFN-g capture ELISA (each tab corresponds to the patient ID). Rights and permissions Reprints and permissions About this article Cite...
The study protocol was approved by the independent ethics committee of the Medical Faculty at the University of Heidelberg. The trial was carried out by adhering to local legal and regulatory requirements. The study complies with the Declaration of Helsinki 2004, the principles of Good clinical ...
The purpose of this first-in-human, open-label, Phase 1 trial (ClinicalTrials.gov, identifier: NCT02157792) was to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary antitumour activity of berzosertib in combination with gemcitabine, with or without cisplatin. ...