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pharmacovigilancewhodefinition 系统标签: definitionadrsdrugpharmacoepidemmedicinesadmissions PharmacovigilanceWHOdefinitionThescienceandactivitiesrelatingtothedetection,assessment,understandingandpreventionofadverseeffectsoranyotherdrug-relatedproblemWhypharmacovigilance?•Humanitarianconcerns–Hippocrates’admonition“atleastdonotha...
These advances provide researchers and regulators with novel tools for acquiring and processing diverse sets of data to identify previously unknown drug interactions, generate hypotheses, and anticipate potential hazards to public health, ensuring that a proactive approach is maintained in drug safety vigil...
While multiple pharmacological drugs have been associated with myocarditis, temporal trends and overall mortality have not been reported. Here we report the spectrum and main features of 5108 reports of drug-induced myocarditis, in a worldwide pharmacovigilance analysis, comprising more than 21 million ...
Definition There are many causes of non-adherence, but they fall into two overlapping categories, intentional and unintentional. Intentional non-adherenceoccurs when the patient decides not to follow the treatment recommendations. Unintentional non-adherenceoccurs when the patient wants to comply...
Phocomelia is very rare in the absence of thalidomide but not vanishingly so; x-irradiation is one example of another cause.[ 1 ] This example is illuminating also because it shows that the definition of the hypothesis is critical: one must be sure one knows what A and B are. In this ...
patient.drug.items.drugintervaldosageunitnumb Number of units in the field `drugintervaldosagedefinition`. Undefined patient.drug.items.drugrecurreadministration Whether the reaction occured after readministration of the drug. 1: Yes, 2: No, 3: Unknown patient.drug.items.drugrecurrence.drugrecuraction...
and enables coding of pharmacovigilance reports using medical terms of the second controlled medical, adverse-event terminology based on a formal definition provided using medical terms of the first controlled medical terminology, wherein the second controlled medical, adverse-event terminology is a Medica...
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When talking about EPV, it is only reasonable to implement that definition to the environment so that EPV can “describe the science and activities associated with the detection, evaluation, understanding and prevention of adverse effects of pharmaceuticals in the environment” [9]. EPV is used to...