Tissues other than peripheral nerves have sodium channels that can be blocked by local anesthetics, and an inadvertently high plasma level of local anesthetic can lead to local anesthetic systemic toxicity (LAST). LAST can manifest as central nervous system toxicity or cardiotoxicity, and treatment ...
This chapter describes the basic chemical structure of local anesthetics, and gives an overview of pharmacologic properties of the different drugs. Clinical use, advantages, and side effects are compared, and local anesthetic toxicity is... HeshamElsharkawy,SreeKolli,HeshamElsharkawy,... 被引量: 0...
Journal: BJA: British Journal of Anaesthesia Keywords: Nerve Block, administration & dosage, Humans, Vasoconstrictor Agents, Bupivacaine, Time Factors, Anesthetics, Local, pharmacology, Anesthesia, Local, Carbon Dioxide, Dextrans, Structure-Activity Relationship ...
The pharmacology of local anesthetics is an integration of the basic physiology of excitable cells and the mechanism by which local anesthetics are capable... JE Tetzlaff - 《Anesthesiology Clinics of North America》 被引量: 91发表: 2000年 Pharmacokinetics of Local Anesthetics Utilizing the pharmacoki...
Local Anesthetics When you go to the dentist to have a tooth pulled, you can thank your lucky stars that local anesthetics are available.Local anestheticsproduce anesthesia, but only in a small area of the body. When they are injected or topically administered, they block the ability of local...
12-2 Molecular structures of local anesthetics 6.5 2 Moderate 200 5 ~ 10 16 bupivacaine 4 ~ 5 16 ropivacaine moderate 2 mepivacaine good 500 1 ~ 2 2 lidocaine amides good surface use only benzocaine good 10 1 2 cocaine good 100 2 ~ 3 10 ~ 2 10 tetracaine poor 100 1 1 1 procaine...
Essentials of Local Anesthetic Pharmacology It is impossible to provide effective dental care without the use of local anesthetics. This drug class has an impressive history of safety and efficacy, b... DE Becker,KL Reed - 《Anesthesia Progress》 被引量: 287发表: 2006年 Pharmacology of local ...
Bao S et al (2022) Neuroimaging mechanism of cognitive behavioral therapy in pain management. Pain Res Manag 2022:6266619–6266619 ArticlePubMedPubMed CentralGoogle Scholar Barreveld A et al (2013) Preventive analgesia by local anesthetics: the reduction of postoperative pain by peripheral nerve bloc...
local anesthetics, 1986. handbook of experimental pharmacology, vol. 81: edited by g.r. strichartz. springer-verlag, new york, berlin, heidelberg, tokyo, pp. 335, bound: dm 224, unbound: dm 280-局部麻醉剂,1986年.药理学实验手册",第一卷. 8... M J.,Dubois - 《Biochimie》 被引量: 0...
1007 Book reviews Protein Compartmentalization, 1986. Springer Series in Molecular Biology, edited by A. W. Strauss, I. Boime and G. Kreil. Springer-Verlag, New York, Berlin, Heidelberg, Tokyo, pp. 140, bound: DM 99 Local Anesthetics, 1986. Handbook of Experimen- tal Pharmacology, Vol. ...