Section:Pharmacology of Anti-Cancer Drugs 强调CircRNA-miRNA-转录因子轴:癌症研究中的一个难题 Accentuating CircRNA-miRNA-Transcription Factors Axis: A Conundrum in Cancer Research 文章导读:环状 RNA(circRNAs)是一类新发现的非编码 RNA,在发育和疾病生物学中起着重要的基因表达调控作用。它们是通过前体 mRNA 转...
本期由目前担任Frontiers in Pharmacology(IF: 4.4 | CiteScore: 7.8) 期刊 Pharmacology of Anti-Cancer Drugs栏目主编的鞠佃文教授,对近期发表在该栏目下的部分文章进行了推荐及点评,此为中上卷,欢迎阅读。 鞠佃文,教授,博士生导师,复旦大学药学院生物药物学系主任,上海免疫治疗药物工程技术研究中心主任。领衔研发中国...
为此,“主编荐读”集合了 Frontiers 众多期刊近期发表的优质文章,由各期刊编委汇总选送。 本期由目前担任 Frontiers in Pharmacology (IF: 4.4 | CiteScore: 7.8) 期刊 Pharmacology of Anti-Cancer Drugs栏目主编的鞠佃文教授,对近期发表在该栏目下的部分文章进行了推荐及点评,此为中上卷,欢迎阅读。 鞠佃文,教授,...
However, with anti-cancer drugs, there are frequently extra factors, not commonly encountered with other drugs, which influence the efficacy of treatment. Such special factors are that many anti-cancer drugs:(a) have a very narrow therapeutic index, i.e. a narrow margin between effective dose ...
(PD-L1) in cancer treat-ment and the need for improving response rates has led to an increased demand for the development of combina-tion therapies with anti-PD-1/PD-L1 blockers as a backbone. As more and more drugs with translational potential are identif i ed, the number of clinical...
Anticancer drug, any drug that is effective in the treatment of malignant, or cancerous, disease. There are several major classes of anticancer drugs; these include alkylating agents, antimetabolites, natural products, and hormones. In addition, there ar
Pharmacology of Anti-Cancer Drugs Pharmacology of Infectious Diseases Pharmacology of Ion Channels and Channelopathies Predictive Toxicology Renal Pharmacology Respiratory Pharmacology Translational Pharmacology The specialty sections of Frontiers in Pharmacology welcome submission of the following article types: Bri...
PHARMACOLOGY OF EMESIS INDUCED BY ANTI-CANCER DRUGS Cancer patients receiving cytotoxic drugs often experience severe nausea and vomiting. Effective antiemetic therapy has not been established. Cisplatin, a ... M Minami,T Endo,Y Monma,... - 《Journal of Toxicological Sciences》 被引量: 4发表: ...
The anti-apoptotic protein MCL1 is a therapeutic target in cancer, but long-term MCL1 inhibition has been found to increase the risk of cardiotoxicity. We developed BRD-810 as a potent and selective MCL1 inhibitor that induces cancer cell death in vivo within a few hours. As BRD-810 was de...
Advancements in new cancer chemotherapies have been improving the prognosis of cancer patients, resulting in a large and rapidly increasing number of cancer survivors. However, their life after cancer is often hindered by unexpected adverse events resulting from anti-cancer therapy. For example, a ce...