Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer. Nutr Rev 2010;68(9):542-55.de-Souza P L,Russell P J,Kearsley J H,et al.Clinical pharmacologyof isoflavones and its relevance for potential prevention of prostate canc-er. Nutrition Reviews . ...
Prostate cancer (PCa) is a cancer that occurs in the prostate with high morbidity and mortality. Danggui Beimu Kushen Wan (DBKW) is a classic formula for patients with difficult urination including PCa. This study aimed to investigate the molecular mecha
For example, symptomatic benign prostatic hyperplasia therapy, while historically treated with primary surgical intervention, is now commonly initially managed with medical therapy. Prostate cancer patients are being treated with newer formulations of long term hormone therapy that range from monthly to ...
A quarter of the 490 proteins of interest in prostate cancer (Prot_PCa) are detectable in LNCaP cells using current mass spectrometry equipment. b For detectable proteins in LNCaP cell lysate SRM assays were developed. Examples of ion chromatograms show four co-eluting transitions with base line...
Androgen receptors in hormone-dependent and castration-resistant prostate cancer. Pharmacology & therapeutics. 2013; 140(3):223-38. doi: 10.1016/j.pharm... AA Shafi,AE Yen,NL Weigel - 《Pharmacol Ther》 被引量: 191发表: 2013年 Current status of inverse agonism at serotonin2A (5-HT2A) and...
The success of antibodies targeting Programmed cell death protein 1 (PD-1) and its ligand L1 (PD-L1) in cancer treatment and the need for improving response rates has led to an increased demand for the development of combination therapies with anti-PD-1/
and for most drugs, age itself is not a contraindication to full-dose chemotherapy. The main limiting factors are comorbidity and poor functional status, which may be present in a significant number of the elderly population. Elderly patients with cancer are part of the daily practice of oncologi...
Network Pharmacology-Based Study on the Mechanism of Aloe Vera for Treating Cancer 来自 掌桥科研 喜欢 0 阅读量: 48 作者:J Xie,J Wu,S Yang,H Zhou 摘要: Background. Aloe vera has long been considered an...
Caution is required when using spironolactone in patients with prostate cancer. Sundar S etal. had reported the case of an 80-year-old man who had heavily pretreated castration refractory carcinoma of the prostate and heart failure. Following the introduction of spironolactone to manage his heart fa...
This phenomenon appears to hold true for the Bmi-1 pathway. Expression profiling on metastatic versus primary prostate tumors from human patients and the murine TRAMP transgenic model revealed substantial elevation of Bmi-1 and its associated molecular signature of 11 genes in metastatic cancer (44)...