Erectile dysfunction (ED) after treatment for prostate cancer (radical prostatectomy, radiotherapy, or androgen deprivation therapy) is common. Systemic therapy with the PDE5 inhibitors is successful in a lower percentage of these patients than it is in men with ED of other etiologies. Penile ...
An insight into a potential new therapy. Dermatol Ther. April 2020:e13365. doi:10.1111/dth.13365 3. Lucas JM, Heinlein C, Kim T, et al. The Androgen-Regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer ...
Unfortunately, advanced colorectal cancer is often present at the time the disease is diagnosed. Many intra-abdominal malignancies spread throughout the pe... H John,Stewart,Perry,... - 《Expert Review of Anticancer Therapy》 被引量: 33发表: 2008年 Laparoscopic interval surgery for stage 4 prim...
Prevalence and predicting factors for commonly neglected sexual side effects to external-beam radiation therapy for prostate cancer. J Sex Med. 2017;14(4):558–65. PubMed Google Scholar Lees JG, et al. Immune-mediated processes implicated in chemotherapy-induced peripheral neuropathy. Eur J ...
Penile rehabilitation therapy following radical prostatectomy is a new area of interest in urology. Preliminary clinical evidence supports the use of early pharmacologic penile rehabilitative therapies; however, large prospective multicenter placebo-controlled trials are needed to determine the benefits and cos...
An update on androgen deprivation therapy for prostate cancer. Androgen deprivation therapy (ADT) with gonadal testosterone depletion is the frontline treatment for advanced prostate cancer. Other hormonal intervention... N Sharifi,JL Gulley,WL Dahut - Endocrine-related cancer 被引量: 345发表: 2010年...
The role of statin therapy in prostate cancer (PCa) prevention and treatment is plagued by controversy. This critical review of published clinical series reveals several caveats in earlier studies, which reported no benefit. Recent studi... AR Last - 《American Family Physician》 被引量: 5发表:...
Targeting the NF-κB Pathway as a Combination Therapy for Advanced Thyroid Cancer NF-κB signaling plays an important role in tumor cell proliferation, cell survival, angiogenesis, invasion, metastasis and drug/radiation resistance. Combination therapy involving NF-κB pathway inhibition is an attractive...
Telomerase as a universal tumor-associated antigen for cancer immunotherapy Although the search for pharmacologic inhibitors of telomerase activity represents a promising approach for telomerase-based anti-cancer therapy, the immun... RH Vonderheide - 《Oncogene》 被引量: 477发表: 0年 Transcription fact...
Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy Polycomb group (PcG) proteins are critical epigenetic mediators of stem cell pluripotency, which have been implicated in the pathogenesis of human cancers... C.,D.,Kemp,... - 《Clinical Cancer Research An Official Journal of...