Plus, Goodman is too busy to be dazzled. In her charge is not only Opdivo, but Opdivo in combination with Yervoy, a complementary cancer immunotherapy first approved in 2011. With a new development team she launched just over a year ago, she’s ushered Opdivo and Yervoy through U.S. and...
After seeing his daughter sit quietly for hours trying to solve puzzles, Eddy’s father bought her a Commodore 64. Starting aged nine, Eddy spent hours on the computer, leading her father, an executive who saw the growing role of IT, to encourage her to pursue the interest further. After ...
Call me™ link will be made active 15 minutes prior to scheduled start time. Webcast:https://viavid.webcasts.com/starthere.jsp?ei=1663864&tp_key=8103bfd962: A replay of the webcast will also be available via Onconova’s investor website approximately two hours after the call’s conclusio...
Today’s featured interview: Craig Snyderspeaking about“Guile” As November approaches, two near opposites clash for the nation's highest office. It's Ven Hess, firebrand populist breaking all the old rules, known as "The Hessian" for his intimidating tactics on the pitcher's mound, versus ...
Tumescent lidocaine solution contains at most 1 g lidocaine and 1 mg epinephrine in 100 mL plus 10 mEq sodium bicarbonate in 10 mL added to 1000 mL of 0.9% physiologic saline for a final lidocaine concentration of 1 g per bag containing 1110 mL or 0.9 g/L (0.09%). Sodium bicarbonate re...
for 3 hours. After the reaction, 10 μL of a Kinase-Glo Plus reagent (Promega, Catalogue No. V3772) was added thereto, and a luminescence was measured with a luminometer. The IC50 value of the compound was calculated, taking the inhibition rate without addition of the enzyme as 100% ...
for 3 hours. The reaction progress was monitored by LCMS analysis. After completion of reaction, the solvent was removed under vacuum and the remanens washed with diethyl ether (3×10 ml) and dried to furnish the crude product (50 mg) as an off-white solid. LCMS: 68%; Desired compound...
48 hours post-transfection, cells were seeded for limited dilution cloning and selected with 1 mg/ml G418 in the culture medium. Following 3 weeks in G418 selection clones were picked and tested in a functional GLP-1 receptor potency assay as described below. One clone was selected for use ...
Best Western Plus Grosvenor Airport Hotel, South San Francisco 16.9 Miles from Atherton The 15th American Healthcare, Hospital Management, Nursing, and Patient Safety Conference is a hybrid event featuring medical consultations, interactive lectures, and quick diagnosis. Participants can... ConferenceMedic...
Abstract: The invention relates to compounds having agonist activity at the GLP-1 (glucagon-like-peptide 1) and GLP-2 (glucagon-like peptide 2) receptors. The compounds find use, inter alia, in the prophylaxis or treatment of intestinal damage and dysfunction, regulation of body weight, and ...