Want to thank TFD for its existence?Tell a friend about us, add a link to this page, or visitthe webmaster's page for free fun content. Link to this page: Facebook Twitter Acronyms browser? ▲ PGCA PGCAA PGCAG PGCAP PGCAR PGCAS ...
Wireless Guide System WAT01-AA From $64.00 (exc. GST) View products Accessories sold separately Wireless Guide System WAT07-EH3 From $64.00 (exc. GST) View products NEWS 2021-03-03 We are happy to assist you in any way. Click here to contact us. Details Here ADVANTAGES One Year Wa...
Drusen, the yellow deposits under the retina, are composed of lipids and proteins, and represent a hallmark of age-related macular degeneration (AMD). Lipid droplets are also reported in the retinal pigment epithelium (RPE) from AMD donor eyes. However, the mechanisms underlying these disease phe...
Dumont M, Stack C, Elipenahli C, Jainuddin S, Launay N, Gerges M, Starkova N, Starkov AA, Calingasan NY, Tampellini D et al. (2014) PGC- 1alpha overexpression exacerbates beta-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease. FASEB...
The FASEB JournalDumont M, Stack C, Elipenahli C, Jainuddin S, Launay N, Gerges M, Starkova N, Starkov AA, Calingasan NY, Tampellini D, Pujol A, Beal MF (2014) PGC-1alpha overexpression exacerbates beta-amyloid and tau deposition in a transgenic mouse model of Alzheimer’s disease....
The impacts of PGC-1α deficiency in hepatocytes on their IL-6 production and macrophage polarization were tested in a Transwell co-culture system. Moreover, the M2-type macrophage polarization and liver fibrosis were examined in hepatocyte-specific PGC-1α knockout mice and AAV8-mediated PGC-1...
already used their Ab against recombinant irisin of known sequence. We eventually mapped the antigen against which the Ab reacts and found it is made against (or at least includes) the last 10 aa of the irisin part of FNDC5. We offered them the data but instead Abcam just withdrew the ...
ThePPARGC1Agene produces two major isoforms of transcriptional coactivators with distinct protein structure, a full-length PGC-1α (797 aa) and a shorter isoform NT-PGC-1α (270 aa)1. Although NT-PGC-1α lacks the C-terminal domain (271–797 aa) of PGC-1α, it can co-activate a nu...
Human PCG-1 alpha is 798 amino acids (aa) in length. It contains an LxxLL nuclear receptor binding motif (aa 144-148), one PPAR-gamma interaction domain (aa 293-339), two NLSs and an RNA binding/processing region (aa 566-710). PGC-1 alpha activity is regulated by phosphorylation. ...
There was a significant association between the A allele and a higher percentage of small dense-LDL particles (GG v GA v AA: 70.8 [58.01–81.06] % v 72.8 [56.18–81.19] % v 78.9 [67.16–85.33] %, p=0.03). In European subjects with T2DM the GA relative to the GG genotype is ...