PGC-1a gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle. FASEB J 2005; 19 (14): 2072–4Southgate,RJ,Bruce,CR,Carey,AL.PGC-1alpha gene expression is down-regulated by Akt-mediated phosphorylation and nuclear ...
The expression of the PGC1Alpha gene is upregulated after birth ...References:Role of PGC-1α signaling in skeletal muscle health and disease. Kang C, Li Ji L Ann N Y Acad Sci. 2012 Oct;1271(1):110-7. doi: 10.1111/j.1749-6632.2012.06738.x. Regulation of peroxisome proliferator-...
LIU R,LI J L,LV X B.Association of PGC-1αgene w ith intramuscular fat content and muscle fiber traits and gene expression in Tibetan pigs.Journal of Animal and Veterinary Advances. 2011Liu, R.,Li, J. L.,Lv, X. B.. Association of PGC-1 alpha gene with intramuscular fat content ...
4. Cho, H., Rambout, X., Gleghorn, M.L., Nguyen, P.Q.T., Phipps, C.R., Miyoshi, K., Myers, J.R., Kataoka, N., Fasan, R., and Maquat, L.E. (2018). Transcriptional coactivator PGC-1alpha contains a novel C...
Gene ID:10891PPARGC1A UniProt:Q9UBK2PPARGC1A 研究领域 肿瘤研究 肿瘤研究 肿瘤代谢研究 代谢科研 代谢科研 肥胖 產品图片 GTX60496 WB Image WB analysis of human PGC1 alpha (AA: 570-798) recombinant protein using GTX60496 PGC1 alpha antibody [1G8]. ...
pgc-1α分子量pgc-1α分子量 PGC-1α(Peroxisome proliferator-activated receptor gamma coactivator-1alpha)是一种转录辅激活因子,它在调节能量代谢、线粒体生物合成和氧化应激反应中发挥重要作用。其分子量约为91.6 kDa。 PGC-1α是由PPARGC1A基因编码的蛋白质。PPARGC1A基因是在基因组上位于4p15.1-p15.3位置,...
ActivAbTM Anti-PGC1 alpha/beta Polyclonal Antibody 亚细胞定位 Nucleus 中文名称 ActivAbTM 过氧化物酶体增殖物激活受体γ辅激活子1α/β Gene ID 10891 储存条件 Store at -20℃. Avoid freeze / thaw cycles. 亚型 IgG 宿主 Rabbit 靶标 PGC1 alpha/beta 别名 PPARGC1A, LEM6, PGC-1(alpha), PGC-1...
Endothelial dysfunction is a characteristic of many vascular related diseases such as hypertension. Peroxisome proliferator activated receptor gamma, coactivator 1α (PGC-1α) is a unique stress sensor that largely acts to promote adaptive responses. The
Down-regulation of GJs and PGC-1alpha gene expression and cellular death were frequently observed in remote viable areas of LV following AMI. Losartan therapy reversed the adverse effects of AMI and preserved LV function. 展开 关键词: Acute myocardial infarction PGC-1< i> α< i> ...
In this study, we hypothesised that polymorphisms in PGC-1alpha downstream targets might also contribute to the variation in the AO. Results In over 400 German HD patients, polymorphisms in the nuclear respiratory factor 1 gene, NRF-1, and the mitochondrial transcription factor A, encoded by ...