产品名称:PGC-1 alpha转录调节剂(ZLN005) 英文名称:ZLN005 产品货号:M05281 产品规格:1mL(10mM)|10mg|50mg ZLN005是新型过氧化物增殖激活受体协同激活子(PGC-1_alpha_)转录调节剂。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途! CAS号:49671-76-3 ...
镰⼑型贫⾎症(Sickle cell disease,SCD)由于β珠蛋⽩基因的单碱基突变导致的,该突变合成的⾎红蛋⽩在低氧条件下极易发⽣聚集,形成多聚体,聚合的⾎红蛋⽩使红细胞呈镰⼑状,镰⼑状的红细胞极易堵塞⾎管,引起组...
PGC-1alpha stimulates the expression of clock genes, notably Bmal1 (Arntl) and Rev-erbalpha (Nr1d1), through coactivation of the ROR family of orphan nuclear receptors. Mice lacking PGC-1alpha show abnormal diurnal rhythms of activity, body temperature and metabolic rate. The disruption of ...
图1. 胶质瘤细胞通过促进PGC1α降解对放疗的抵抗,减少线粒体生物合成,可能是增强放射敏感性的潜在治疗策略。 研究结果 过氧化物酶体增殖物激活受体-γ共激活因子1α(peroxisome proliferator-activated receptor-gamma coactivator 1 alpha,...
首先,PGC1α可通过增加脂肪酸摄取和转运的基因表达水平来提高细胞内脂肪酸浓度,从而促进脂肪酸β氧化过程。其次,PGC1α可以与核受体PPAR α(peroxisome proliferator-activated receptor alpha)相互作用,并共同启动一系列脂肪酸代谢相关的基因转录,包括参与脂肪酸β氧化的关键酶。 此外,研究还发现PGC1α可通过调节线粒体...
2 results for "PGC1 alpha ELISA Kits" in Products Sort by: PGC1 alpha: ELISA Kits PGC-1alpha (peroxisome proliferator-activated receptor gamma coactivator 1 alpha), also known as PPARGC1A, belongs to a family of PPAR coactivators. It facilitates mitochondrial DNA synthesis, thus regulating ...
View 1 PGC1 alpha Proteins and Enzymes. Bio-Techne offers high-quality reagents, instruments, custom manufacturing and testing services.
产品名称 :Recombinant Human PGC1 alpha 货号:P-Db4160 宿主:E.Coli 标签:N-terminal His Tag 规格: 50μg, 200μg, 1mg 种属:Human 表达区间:481-798 分子量:34.9 kDa 纯度:Greater than 95% as determined by SDS-PAGE 应用:Western Blot, ELISA ...
Buy PGC1 alpha Polyclonal Antibody suitable for WB;IF and reacts with Human;Mouse;Rat samples. Cited in 7 publications.
PGC-1α(全称:Peroxisome proliferator-activated receptor γ coactivator 1-alpha)是一种转录共激活因子,是关键的调节能量代谢和适应性修复过程的蛋白质。它在许多生物学过程中发挥重要作用,包括线粒体生物发生、有氧呼吸、糖原合成和肌肉适应性。PGC-1α的分子量约为91 kDa。 PGC-1α在人类和小鼠中均有表达,并...