There has been presented a case of effective treatment of Peutz–Jeghers syndrome — diffuse polyposis of small and large intestines combined with melanotic skin pigmentation. Multiple enteric intussusception revealed during the surgery was eliminated when removing polyps. There have been described ...
《中国小肠镜诊治 Peutz‑Jeghers 综合征的 专家共识意见(2022 年)》的出台背景 黑斑 - 息肉综合征(Peutz ‑ Jeghers syndrome, PJS)是一种罕见的常染色体显性遗传性肿瘤综合 征,其主要特征为皮肤黏膜色素沉着,胃肠道多发 错构瘤性息肉和肿瘤易感性.尽管 PJS 是一种罕 见疾病,但我国是人口大国,发病人数仍然...
(Peutz⁃Jeghers syndrome,PJS)是一种常染色体显性遗传疾病,以皮肤 黏膜色素沉着,胃肠道多发错构瘤性息肉和肿瘤易感性为主要特征.小肠是 PJS 息肉好发部位之一, 易伴发肠套叠,肠梗阻,消化道出血,癌变等并发症.随着小肠内镜技术的迅速发展,小肠镜已经成为 PJS 诊治的关键技术,在小肠息肉诊断及治疗中发挥重要作用....
黑斑息肉综合征(Peutz-Jeghers syndrome, PJS)又称家族性黏膜皮肤色素沉着胃肠道息肉病,是一种常染色体显性遗传病,以皮肤黏膜色素沉着、胃肠道多发息肉为主要特点。患病率为1/200000～1/8000。患者胃肠道息肉发生癌变风险较高,需要定期监测、规律随诊、及时治疗。黑斑息肉综合征是一种常染色体显性遗传疾病,大部分与...
peutz⁃jeghers综合征;小肠镜;指南解读 一,《中国小肠镜诊治peutz⁃jeghers综合征的专家共识意见(2022年)》的出台背景 黑斑 -息肉综合征(pjs)是一种罕见的常染色体显性遗传性肿瘤综合征,其主要特征为皮肤黏膜色素沉着,胃肠道多发错构瘤性...
Jeghers syndrome, and Double-balloon enteroscopy has important clinical significance in the diagnosis and treatment of it. With the developing of translational medicine, molecular targeted therapy brings a new paproach to preventive treatment of gastrointestinal polyposis of Peutz-Jeghers syndrome, and the...
Advances in the prevention, diagnosis and treatment of Peutz-Jeghers syndrome. Shijie Huaren Xiaohua Zazhi 2011; 19(30): 3111-3116摘要Peutz-Jeghers综合征(Peutz-Jeghers syndrome, PJS)以皮肤黏膜色素斑、胃肠道错构瘤息肉和遗传性为临床特征. PJS胃肠道息肉可产生梗阻、出血、套叠、恶变等严重并发症, 目前...
Peutz-Jeghers综合征(Peutz-Jeghers syndrome,PJS)是一种临床上罕见的常染色体显性遗传综合征,发病率为1/50 000~1/200 000[1]。PJS在中国的发病率据估算为1/140 000左右[2],中国可有7 000~28 000例PJS患者。主要临床表现为多发的...
Jeghers syndrome. MethodsFrom January 2000 to December 2010,71 cases of Peutz-Jeghers syndrome underwent endoscopic polyp resection fi rstly,and those with unresectable lesions or with severe complications underwent rescue laparotomy. After endoscopic or surgical treatment,the patients took Celecoxib ...
Research progress on genotype,clinical diagnosis and treatment of Peutz-Jeghers syndrome 引用 收藏 分享 摘要 Peutz-Jeghers综合征(PJS)是一种临床罕见的常染色体显性遗传病,该病以皮肤黏膜色素斑、胃肠道多发错构瘤息肉和家族遗传性为特征性临床表现,其罹患恶性肿瘤的发生率明显高于正常人群。该病的分子发病机制与...