Peroxisomes are organelles that carry out β-oxidation of fatty acids and amino acids. Both rare and prevalent diseases are caused by their dysfunction1. Among disease-causing variant genes are those required for protein transport into peroxisomes. The p
2016. Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants. Biochim Biophys Acta Mol Cell Res 1863: 850-62.Cross, L.L., Ebeed, H.T. and Baker, A. (2016) Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants. Biochim. Biophys. ...
Peroxisome biogenesis disorder protein 1 peroxisome biogenesis factor 1 peroxisome biogenesis factor 10 peroxisome biogenesis factor 13 peroxisome biogenesis factor 16 peroxisome biogenesis factor 2 peroxisome biogenesis factor 6 peroxisome proliferative activated receptor, alpha ...
Isolation of Penicillium chrysogenum PEX1 and PEX6 encoding AAA proteins involved in peroxisome biogenesis. Appl. Microbiol. Biotechnol. 54, 238–242 (2000). Article CAS PubMed Google Scholar Purdue, P. E. & Lazarow, P. B.Peroxisome biogenesis. Annu. Rev. Cell Dev. Biol. 17, 701–752 ...
Brefeldin A interferes with peroxisomal protein sorting in the yeast Hansenula polymorpha We have studied the effect of brefeldin A (BFA), a fungal toxin that interferes with coated vesicle formation, on the biogenesis of peroxisomes in the yeas... FA Salomons,IJVD Klei,AM Kram,... - 《Febs...
In this review article, we summarize current knowledge on peroxisome biogenesis/functions and the role that small GTPases may play in these processes. Precise intracellular distribution of cell organelles requires their regulated association to microtubules and the actin cytoskeleton. In this respect, Rh...
Investigations of peroxisome biogenesis in diverse organisms reveal new details of this unique process and its evolutionary conservation. Interactions among soluble receptors and the membrane peroxins that catalyze protein translocation are being mapped. Ubiquitination is observed. A receptor enters the organe...
Lazarow PB, Fujiki Y (1985) Biogenesis of peroxisomes. Annu Rev Cell Biol 1:489–530 Article CAS PubMed Google Scholar Lee A et al (2014) Role of NH2-terminal hydrophobic motif in the subcellular localization of ATP-binding cassette protein subfamily D: common features in eukaryotic organisms...
Some mysteries about peroxisomal matrix protein import disclosed? Novel peroxins Peroxisome biogenesis depends on peroxins (PEX proteins), which are essential for peroxisome formation and include proteins of the import machineries for matrix and membrane proteins as well as proteins involved in peroxisome...
Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders The peroxisome biogenesis disorders (PBDs) are a group of lethal autosomal-recessive diseases caused by defects in peroxisomal matrix protein import, with ... BE Reuber,E Germain-Lee,CS Collins,... - 《Nature ...