Peroxisome biogenesis disorder protein 1 peroxisome biogenesis factor 1 peroxisome biogenesis factor 10 peroxisome biogenesis factor 13 peroxisome biogenesis factor 16 peroxisome biogenesis factor 2 peroxisome biogenesis factor 6 peroxisome proliferative activated receptor, alpha ...
Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants [J]. Biochimica et Bio- physica Acta (BBA)-Molecular Cell Research, 2016, 1 863(5): 850-862.L. L. Cross, H. T. Ebeed, and A. Baker, "Peroxisome biogenesis, protein targeting mechanisms and PEX gene ...
Peroxisomes are organelles that carry out β-oxidation of fatty acids and amino acids. Both rare and prevalent diseases are caused by their dysfunction1. Among disease-causing variant genes are those required for protein transport into peroxisomes. The p
Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders The peroxisome biogenesis disorders (PBDs) are a group of lethal autosomal-recessive diseases caused by defects in peroxisomal matrix protein import, with ... BE Reuber,E Germain-Lee,CS Collins,... - 《Nature Genetics...
Figure 1. Model of peroxisomal matrix protein import. (I) Proteins harboring a peroxisomal targeting signal of type 1 (PTS1) are recognized and bound by th... EH Hettema,R Erdmann,IVD Klei,... - 《Current Opinion in Cell Biology》 被引量: 112发表: 2014年 Peroxisome biogenesis: Where Ar...
We have cloned a cDNA encoding a 35-kDa peroxisomal integral membrane protein (termed peroxisome assembly factor-1, PAF-1) that restores peroxisome biogenesis and complements the defects of peroxisomal functions in the mutant Z65. 展开 关键词:...
(ADHAPS, 2q31). In a human cell, the number of peroxisomes vary from less than 100 to more than 1000. In yeast either over expression or lacking the Inp 1 protein (inheritance of peroxisome protein 1) are detrimental for the right amount and the proper distribution of peroxisome. Inp ...
Brefeldin A interferes with peroxisomal protein sorting in the yeast Hansenula polymorpha We have studied the effect of brefeldin A (BFA), a fungal toxin that interferes with coated vesicle formation, on the biogenesis of peroxisomes in the yeas... FA Salomons,IJVD Klei,AM Kram,... - 《Febs...
The peroxisomes have indispensable roles in fatty acid β oxidation, phospholipid and cholesterol metabolism. Fatty acid granules are also named microbodies. The peroxisome biogenesis disorders (PBD) are recessive lethal diseases in variable forms. The extreme form is th ... 展开 ...
Some mysteries about peroxisomal matrix protein import disclosed? Novel peroxins Peroxisome biogenesis depends on peroxins (PEX proteins), which are essential for peroxisome formation and include proteins of the import machineries for matrix and membrane proteins as well as proteins involved in peroxisome...