However, the molecular basis for the lower percent of free PSA in patients with prostate cancer remains unknown, and considerable overlap in values exists. We examined this hypothesis in men with recurrent or persistent cancer after radical prostatectomy. These men, who have "pure" cancer in that...
John G Phillips, Ming-Hui Chen, Danjie Zhang, Marian Loffredo, Philip W Kantoff, Anthony V D’Amico. (2014) Percent positive biopsy cores and the risk of death from prostate cancer in men with unfavorable-risk prostate cancer. Journal of Radiation Oncology 3 , 307-312 /...
Patients with prostate cancer may have more of the complexed form of prostate-specific antigen (PSA) in the serum, whereas patients with benign prostatic hyperplasia have less of this complexed form and thus a higher proportion of the free form. However, the molecular basis for the lower ...
1987) as a serum marker for prostate cancer and its subsequent development as a screening test for early detection (Catalona et al. N Engl J Med 324(17):1156–61, 1991) dramatically altered the diagnosis and management of this disease. PSA correlated directly with prostate cancer risk and, ...
Prostate cancer Diagnosis Prostate-specific antigen Percent free PSA Chinese population ROC curve 1. Introduction Prostate cancer (PCa) is the second-most frequently diagnosed malignancy in men globally [1]. Although the incidence of PCa in China is much lower than in Western countries [2], PCa ...
Percent free prostate specific antigen and cancer detection in black and white men with total prostate specific antigen 2.5 to 9.9 ng./ml. The ratio of free-to-total prostate specific antigen (PSA), or percent free PSA, is a useful adjunct to total PSA for estimating the risk of prostate ...
Testosterone Is Associated With High-grade Prostate Cancer in Men Undergoing Prostate BiopsyObjective To analyze the serum androgen concentrations in men who underwent an initial prostate biopsy, focusing on the percent-free testosterone (%FT) as a predictor of low- and high-grade prostate cancer (...
We investigated the usefulness of percent free prostate specific antigen for detecting prostate cancer in Korean men. A total of 1,528 men with a palpably benign prostate gland and prostate specific antigen 4.0 to 10.0 ng/ml underwent prostate biopsy at 25 hospitals in Korea. Patients were catego...
Edwards SM, Kote-Jarai Z, Meitz J, et al. Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene. Am J Hum Genet 2003;72:1.Boetes C. Update on screening breast MRI in high-risk women. Magn Reson Imaging Clin N Am. 2010; 18 :241–247. ...
Percent free prostate-specific antigen for prostate cancer diagnosis in Chinese men with a PSA of 4.0-10.0 ng/ml: Results from the Chinese Prostate Cancer Consortium. Asian J Urol. 2015; 2 (2):107-13.CHEN R,XIE L,CAI X,et al.Percent free prostate-specific antigen for prostate cancer ...