Peptide-based synthetic vaccinesIJARIIEvaibhavi
1. Arnon, R. and Levi, R. Synthetic recombinant vaccine induces anti-influenza long-term immunity and cross strain protection, In:Novel Strategies in Design and Production of Vaccines(Ed.: Cohen, S. and Shafferman, A.) Plenum Press, N.Y., 1996, p. 23. ...
Synthetic peptides represent an attractive source of antigen to stimulate T cell immunity in animals and humans [2]. They have a number of advantages over whole protein vaccines including improved specificity, purity, safety, low-toxicity, ease of manufacture/characterisation, and lower cost of good...
Whole organism-based vaccine has some danger signal and protein associated with it, so, peptide-based vaccines come into picture as they are intrinsically more safer, avoid any nonprotective response, immune evasion, and side effects in terms of autoimmunity (Reche, Flower, Fridkis-Hareli, & ...
This review will focus on peptide-based, fully synthetic vaccines that aim to overcome many of the pitfalls of conventional ones. We start with a general survey of epitope-based vaccines and spotlight foot-and-mouth disease virus (FMDV) as a model for peptide-based vaccine development. In ...
In this regard, subunit vaccines devoid of infectious agent, particularly those based on synthetic peptides, have arisen as an attractive alternative due to their multiple advantages including safety, marker nature, fine-tuning to different strains, and easy handling, shipping and storage [9,10]. ...
Anticancer peptides (ACPs) perform a promising role in discovering anti-cancer drugs. The growing research on ACPs as therapeutic agent is increasing due to its minimal side effects. However, identifying novel ACPs using wet-lab experiments are generally
vaccine inequity and the need for booster doses to restore the vaccine effectiveness make it clear that the battle against this notorious virus is far from over [15]. In this context, efforts are required to be directed towards the development of new vaccines that can elicit durable protection...
Autologous monocyte-derived dendritic cells (DCs) electroporated with synthetic messenger RNA (mRNA) encoding a CD40 ligand, a constitutively active Toll-l... S Wilgenhof,AMT Van Nuffel,D Benteyn,... - 《Annals of Oncology Official Journal of the European Society for Medical Oncology》 被引量...
Synthetic pep-tide-based vaccines that target functionally relevant motifs such as the receptor binding domain (RBD) of the pilin protein of Pa, which is responsible for bacterial adhesion to host receptors, are a novel alternative to traditional vaccines and antibiotics to combat Pa infec-tion. ...