Pharmacokinetics and Pharmacodynamics of Single Doses of Subcutaneous Pegylated Human GCSF Mutant (PEG30-rhG-CSF) in Beagle dogs[J].Journal of Clinical Oncology,2008,(05):326-332.Cai YM,Chen ZM,Jiang L. Pharmacokinetics and Pharmacodynamics of Single Doses of Subcutaneous Pegylated Human GCSF ...
PEG-filgrastim has been used at Children's Hospital at Westmead (CHW) since December 2002. At CHW we mobilise and harvest PBSC's from approximately 35 patients per annum following colony stimulating factors, predominantly GCSF +/- chemotherapy. We observed that in 5 patients after routine ...
Banks and co-workers investigated the relationship between the native state solubility determined via kosmotrope- or PEG-precipitation and the aggregation rate of IgGs as well as rhGCSF [36], [37], [38]. Excipients that increased the solubility of the proteins simultaneously decreased the aggregati...
Pharmacokinetics and Pharmacodynamics of Single Doses of Subcutaneous Pegylated Human GCSF Mutant (PEG30-rhG-CSF) in Beagle dogs[J].Journal of Clinical Oncology,2008,(05):326-332.Yongming Cai et al.Pharmacokinetics and pharmacodynamics of subcutaneous single doses of pegylated human G-CSF mutant(...
Pharmacokinetics and Pharmacodynamics of Single Doses of Subcutaneous Pegylated Human GCSF Mutant (PEG30-rhG-CSF) in Beagle dogs[J].Journal of Clinical Oncology,2008,(05):326-332.Cai YM,Chen ZM,Jiang L. Pharmacokinetics and Pharmacodynamics of Single Doses of Subcutaneous Pegylated Human GCSF ...