PEEP is of greatest use in ARDS and generated by attaching an airflow threshold resistance device to the expiratory port of the non-rebreathing valve of a manual or mechanical ventilator, allowing a ↓ of airway pressure to a plateau level Conventional PEEP Pressure is maintained at 5-20 cm ...
(1) a PEEP level of 12 cm H2O with alveolar recruitment maneuvers performed after endotracheal intubation, which were repeated every hour after any disconnection from the mechanical ventilator and before the end of surgery (high level of PEEP group) or (2) a PEEP level of 4 cm H2O (low ...
In this study, ventilator-driven alveolar lung recruitment will be performed using the incremental PEEP method with the target PEEP set at 20 cmH2O and the target Ppeak set at 40 cmH2O. Individualized PEEP will be obtained by Cstat titration in obese patients. The effect of iPEEP on perioper...
On each level of PEEP, ABGs will be collected and evaluated. Optimal PEEP is considered as the PEEP value resulting the highest possible Cstat measured by the ventilator. After the PEEP titration procedure, lung-protective mechanical ventilation will be performed using optimal PEEP and low tidal ...
Expiratory flow limitation was associated with both high and complete “PEEP-absorber” behavior, but setting a relatively high respiratory rate on the ventilator can prevent from observing complete “PEEP-absorption.” Therefore, the effect of PEEP application in patients with auto-PEEP can be accura...
Conclusion: The adjustment of PEEP and FiO2 based on PaO2 is effective in reducing the disease severity score duration of ventilator connection, and ICU stay. It should be used as a nursing intervention in coordination with treatment team to reduce the consequences of hospitalization in ICU....
(IQR 7.5, 53.6) with a severity of Pediatric Acute Respiratory Distress Syndrome that ranged from mild to severe with a median lung injury score of 2.3 (IQR 2.0, 2.7).Measurements: Cardiac index (CI) and stroke volume (SV) were measured on baseline ventilator settings and subsequently with ...
This randomized trial compares the effects of ventilator lung recruitment using PEEP titration vs a conventional low-PEEP strategy on 28-day mortality in
These suggest a greater degree of lung recruitment was sustained throughout the study period in the PHARLAP group, an effect which may be important in ARDS to minimise the potential negative effects of ventilator induced lung injury. Systemic arterial oxygenation, as measured by the PaO2/FIO2, ...
However, assuming the mortalities attributable to ventilator-induced lung injury is 10% would indicate that all deaths due to ventilator-induced lung injury "would need to be avoided by using the esophageal pressure-guided PEEP titration compared with the empirical high PEEP-FIO2 table," they noted...