BACKGROUND Oncology patients are frequent recipients of prophylactic platelet transfusions. Recent studies have demonstrated that lower prophylactic doses of platelets were not associated with a higher incidence of bleeding. At our institution, we found wide variation in platelet dosing due to lack of ...
Neonatal platelet transfusions. There are few evidence-based studies of platelet transfusions in neonates with the asso- ciation between thrombocytopenia and bleeding remaining unclear. In one study with 58 infants, only two infants with IVH had low platelet counts and prolonged bleeding, and two ...
Aggressive supportive care with erythrocyte and platelet transfusions is necessary and transfusion thresholds are higher for patients with SCD than other HSCT patients (89). Additionally, avoid- ance of hypertension and hypomagnesemia are especially important to avoid neurologic sequelae in the immediate ...
Full Issue Original Article Retrospective Analysis of Transfusion-Related Adverse Reactions: A 15-Month Study of a Single Center’s ExperienceTransfusion-Related Adverse Reactions Abstract views:227 Şule Çalışkan Kamış, Defne Ay Tuncel, Ganiye Begül Küpeli ...
•Prophylactic platelet transfusions for children undergoing cancer treatment are not well characterized and require further investigation.•The effect of routine platelet transfusion in pediatric cardiac surgery on postoperative outcome is unknown.•The determination of platelet count threshold before vario...
Platelet engraftment is defined as achieving a platelet count ≥ 20 × 109 /L without transfusion support for 7 consecutive days. Myeloablative conditioning regimen, defined as Bu > 8 mg/kg. Viral DNA ≥ 500 copies/mL in plasma was defined as viremia for cytomegalovirus (CMV...
Prior data indicated that 38% of those who required platelet transfusion were free of transfusion following the third cycle of therapy. Of the 17 patients who went on to undergo HSCT, 82% were leukemia free at a median follow-up of 23.8 months (range, 7.0-39.3). Regarding safety...
Intraoperative volumes of platelet transfusion that failed to increase a postoperative TEG-MA of at least 45 mm significantly increased the risk for postoperative bleeding in the first 24 hours after surgical procedures (odds ratio, 3.2; 95% CI, 1.9-5.4;P< .01 [significantPvalue <.05]). The...
Major bleeding is clinically overt bleeding associated with a decrease in hemoglobin of ≥2 g/dL, a transfusion of ≥2 units of packed red blood cells or whole blood, or bleeding at a critical site or with a fatal outcome. CVC-VTE = central venous catheter–related venous thromboembolism; ...
Patients with IPDs require different education about their disorder and, in comparison with ITP management, platelet transfusions are an important therapeutic agent for significant bleeding or in preparation for surgery, although this must be balanced with the risk of alloimmunization with platelet ...