Pediatric nonclinical drug testing: principles, requirements, and prac- tices. Wiley, 2012, pp. 255-279.Hoberman, A. 2012. Pediatric non-clinical drug testing principles, requirements, and practice. Wiley, Hoboken, NJ.Lewis EM, De Schaepdrijver LM, and Coogan TP. Intro- duction. In: ...
We developed ePOCT+, a digital clinical decision support algorithm in combination with C-reactive protein test, hemoglobin test, pulse oximeter and mentorship, to guide health-care providers in managing acutely sick children under 15 years old. To evaluate the impact of ePOCT+ compared to ...
(The British Forum for the Use of Medicines in Childhood, 1998). It has been said, 'When the USA sneezes, Europe catches a cold.' On 2 December 2000, it became mandatory in the USA that all new drug applications (NDAs) and some biological ones must contain a pediatric component if ...
Mutations are color-coded by call status, where Both is called in both assays and ITH is mutations that were not called in higher- depth resequencing and/or had proportion test p-value < 0.05. e Barplot demonstrating breakdown of MSK-IMPACT mutations, observed in both WGS and MSK-...
Adverse Drug Reaction Monitoring in Pediatric Practice NA Kshirsagar,S Karande 被引量: 0发表: 1997年 Adverse drug reaction monitoring of ciprofloxacin in pediatric practice. Ciprofloxacin, a fluoroquinolone antibacterial agent, is not recommended in pediatric population on account of its possible adverse...
The Pediatric Symptom Checklist (PSC) (see Appendix) was developed as a screening test for psychosocial dysfunction among school-age children seen in general pediatric practice. While in the waiting room, the parent is asked to complete a 35-item list of symptoms by approximating their occurrence...
Codeine is a drug that remains in world-wide clinical usage despite the availability of other opi-oids that are far better understood in terms of pharmacodynamics, pharmacokinetics, and side effects. Its continuing usage in clinical practice highlights a paradoxical inconsistency in the prescribing habi...
Elevated troponin levels in previously healthy children: value of diagnostic modalities and the importance of a drug screen. Cardiol Young 2014;24:283–9. https://doi.org/10.1017/s1047951113000231.Search in Google Scholar PubMed 11. Harris, TH, Gossett, JG. Diagnosis and diagnostic modalities ...
(37.1 to 272.2 mL/min), mild hepatic impairment, ECOG performance status, antidrug antibody (ADA), body weight, sex, and baseline albumin. These factors were found to have no clinical meaningful effect on the PK of sintilimab (https://www.fda.gov/media/156022/download;https://img....
In still others, however, some of those who have not taken drug in- jections themselves and have had intimate exposure to patients with serum hepatitis have had hepatitis. I have been encouraged to believe that patients with serum hepatitis may transmit infection, doubtless by fecal contamination...