Finding the right PDX model for your breast cancer or melanoma research requires: Accuracy: Work with a model that has the genotype/phenotype you want to target High fidelity: Choose a model that does not drift (or has minimal drift) genetically from the original tumor ...
Engineering liquid metal-based nanozyme for enhancing microwave dynamic therapy in breast cancer PDX model DOI:10.1186/s12951-023-02121-9 文献摘要:微波动力治疗(MDT)的新理念解决了临床上微波热疗(MWTT)非选择性加热、温度分布不均匀导致肿瘤根除不彻底,微波敏化剂输送不畅和肿瘤缺氧障碍的问题。在此,我们设计...
significant progress has been made in platinum-based combination chemotherapy. However, the five-year survival rate of patients with advanced ovarian cancer has not improved significantly in the past 30 years. The tumor cell line model, a dru...
[7]Cells 2019, 8, 889; doi:10.3390/cells8080889 [8] DeRose YS, Wang G, Lin YC, Bernard PS, Buys SS, Ebbert MT, Factor R,Matsen C, Milash BA, Nelson E, et al. Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease ...
Conclusion: The synthesized nanozyme effectively solves the defects of MDT, improves the targeted delivery of microwave sensitizers while regulating the hypoxic microenvironment of tumors, and achieves excellent MDT effect in the constructed PDX model, providing a new strategy for clinical cancer treatment...
Recent progress in patient-derived tumor xenograft model of breast cancer. Sci Sin Vitae, 2016, 46: 695–704, doi: 10.1360/N052015-00386 © 2016《中国科学》杂志社 www.scichina.com https://engine.scichina.com/doi/10.1360/N052015-00386 马丽君等: 人乳腺癌 PDX 模型的研究进展 型遗传学...
原文标题: A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response
马丽君, 战军, 张宏权. 人乳腺癌PDX模型的研究进展. 中国科学: 生命科学, 2016, 46: 695–704 Ma L J, Zhan J, Zhang Y Q. Recent progress in patient-derived tumor xenograft model of breast cancer. Sci Sin Vitae, 2016, 46:695–704, doi: 10.1360/N052015-00386...
Establishment of a patient⁃derived orthotopic Xenograft ( PDOX) model of HER⁃2⁃ positive cervical cancer expressing the clinical metastatic pattern [ J] . PLoS One, 2015, 10(2) : e0117417. [35] Cho SY, Kang W, Han JY, et al. An integrative approach to precision cancer medicine...
Cancer animal models over the years. The animal model of cancer was first introduced in 1918, but the beginning of today’s models was in 1951 with the development of the CDX models, but the development of other models led to competition for a more suitable model with more efficiency. The...