TREHANPATI N,VYAS AK.Immune regulation by T regulatory cells in hepatitis B virus-related inflammation and cancer[J].Scand J Immunol,2017,85( 3) : 175-181. PENG JP,SUN KW,WU YN,et al.Programmed cell death 1 expression on HBV-specific CTLs induced by dendritic cells in chronic hepatitis...
在小鼠肿瘤模型中, anti-TIGIT 抗体通过 FcγR-Fc 作用激活肿瘤微环境里的髓系细胞(macrophages, monocytes, 和 dendritic cells)并最终改变抗肿瘤 CD8+ T 细胞的细胞状态(from an exhausted effector-like to memory-like state)。这...
PDL1 expression on plasma and dendritic cells in myeloma bone marrow suggests ben- efit of targeted anti PD1-PDL1 therapy. PLoS One. 2015;10(10): e0139867.Sponaas AM, Moharrami NN, Feyzi E, Standal T, Rustad EH, Waage A, et al. PDL1 expression on plasma and...
[4].Kim C Ohaegbulam, Amer Assal, Eszter Lazar-Molnar, et al. Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway[J]. Trends Mol Med. 2015 Jan;21(1):24-33. [5].Maud Mayoux, Andreas Roller, Vesna Pulko, et al....
Exosomes derived from dendritic cells improve cardiac function via activation of CD4+ T lymphocytes after myocardial infarction. J. Mol. Cell Cardiol. 91, 123–133 (2016). CAS PubMed Google Scholar Arslan, F. et al. Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative...
1.hansenm,meto,svaneim,andersenmh.cellularbasedcancervaccines:type1polarizationofdendriticcells.currmedchem2012;19:4239-4246. 2.tamurah,dongh,zhug,sicagl,fliesdb,tamadaketal.b7-h1co-stimulationpreferentiallyenhancescd28-independentt-helpercellfunction.blood2001;97:1809-1816. ...
cellsinthe peripheral bloodof PulmonaryTuberculosis patients. Methods‘Subsetsofdendriticcellsand T--helper cellsinthe peripheral bloodwere detected by flow cytometry in63 preliminarydiagnosedPulmonary Tuberculosis patients and30 healthydonors.HLA-DR+CDl23+(DC2)andHLA-DR+CDllc+(DCl)、 CD4+几14+(Th2)...
(p<0.05). The gene mutation rate of VDR in COAD was 2 %. OS and DFS were not associated with changes in the VDR gene in patients with COAD. VDR expression was correlated with CD4+T cell infiltration, macrophage infiltration, neutrophil infiltration, and dendritic cell infiltration. VDR ...
The priming and activation of effector T-cells with specificity for tumor antigen is carried out by APCs such as dendritic cells (DCs). Constitutively patrolling the blood, peripheral tissues, lymph, and secondary lymphoid organs, DCs sample the extracellular environment and phagocytose self- and ...
Physiologically, activated B and T cells; macrophages and histiocytes; and dendritic cells express PD1 on their surface [42]. In the current study, PD1 and PDL1 expres- sion was observed mainly on macrophage and histiocytes in the background of tumor. Conclusion The findings of the present ...