PDE4 inhibitors restore intracellular stability (homeostasis) of pro-inflammatory and anti-inflammatory signals by inhibiting the activity of PDE4. Phosphodiesterase-4 is an enzyme that breaks down signaling molecules known as cyclicadenosinemonophosphate (cAMP), which modulate immune responses. Inhibition ...
翻译结果4复制译文编辑译文朗读译文返回顶部 翻译结果5复制译文编辑译文朗读译文返回顶部 相关内容 a: either point to point or point to multipoint services; : 点对点或单点到多点服务; [translate] aMake a list of the names of all the people who can mean something to you 做名单能意味某事对您所有人...
A review was here made about the common methods for detecting the illegally-added phosphodiesterase-5 inhibitors (PDE-5i) and analogues in healthcare food, having enumerated physical and chemical rapid screening, enzyme-linked immunosorbent assay (ELISA), gold immunochromatography assay (GICA), near ...
1. This list refers to pyridine compounds used as therapeutic agents for central nervous system disorders related to phosphoric acid 10. This report also deals with the use of these compounds in the treatment of neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's...
Also claimed are pharmaceutical compositions, the use of the compounds as PDE4 inhibitors, and combinations with other actives. </ListItem></UnorderedList></ListItem></UnorderedList> 展开 收藏 引用 批量引用 报错 分享 全部来源 求助全文 掌桥科研 参考文献...
In addition, the scientific community is giving particular attention to other pharmaceuticals not yet on the Watch list, whose markets are in growth; particularly, the Phosphodiesterase 5 (PDE-5) inhibitors used for the pharmaceutical treatment of erectile dysfunction (ED) in men. This review ...
ABT-888 inhibitor The discoveries from this work could be foundational for the creation of novel anticancer agents, focusing on VEGFR-2 inhibitors that are capable of targeting multiple molecules.The mycotoxin gliotoxin, produced by Aspergillus fumigatus, manifests a variety of pharmacological effects,...
The general purpose of the study is evaluate the non-inferiority hypothesis for ischemic events and the superiority hypothesis for bleeding events resulting from platelet P2Y12 receptor inhibitors given as monotherapy in comparison with conventional dual antiplatelet therapy in acute coronary syndrome ...
For that reason, the PDE3 was called the cGMP-inhibited PDE to distinguish it from PDE4.[1] The 44-amino acid insertion in the catalytic domain of PDE3s is believed to be involved in PDE3's interaction with its substrate and inhibitors, but that remains to be established.[1] The ...
subtypes of basal cell carcinoma (BCC) and their distribution across the body. There's been a lack of published material regarding the nature of secondary tumors. With the arrival of newer medical treatments, like hedgehog inhibitors, a better comprehension of the genetics underlying BCC is ...