参考文献 Philip Bischoff et al., Outcome of first-line treatment with pembrolizumab according to KRAS/TP53 mutational status for non-squamous PD-L1 high (≥50%) NSCLC in the German National Network Genomic Medicine Lung Cancer (nNGM), Journal of Thoracic Oncology, 2023.
妇科肿瘤一直是危害女性健康的重大疾病隐患。宫颈癌发病率最高,与HPV感染密切相关。子宫内膜癌发病隐秘,类型复杂。卵巢癌深藏盆腔深部,不易察觉,且中青年高发。近年来三大癌种的治疗进展发展缓慢,新药寥寥,那随着PD1单抗在国内的上市使用,这三类癌种的患者能否使用PD1呢?疗...
Statistical analyses revealed dependencies of the PD-L1 status and the categories of age, grading and histopathology. These results were not consistent when using the different scores IC, TPS or CPS, as depicted in Table 3. Further survival results for PD-L1-positivity are listed in the ...
[1]王也,笪冀平,王德文.EGFR突变型非小细胞肺癌中PD-1、PD-L1表达的研究进展[J].诊断病理学杂志,2017,24(03):223-226. [2]Li Jing,Gu Jian. PD-L1 expression and EGFR status in advanced non-small-cell lung cancer patients ...
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2. Sung Won Lim,Myung-Ju Ahn. Current status of immune checkpoint inhibitors in treatment of non-small cell lung cancer. 2018.7. 福利到! 目前,我司对接多个免费肺癌的免疫治疗临床试验,包括国产及进口PD1,有意可以文末扫码进群报名。©2022 Baidu |由 百度智能云 提供计算服务 | 使用百度前必读 | ...
最近在JAMA Network Open(IF 5.08)发表的一篇真实世界的回顾性研究“Association ofProgrammed Cell Death Ligand 1 Expression Status With Receipt of ImmuneCheckpoint Inhibitors in Patients With Advanced Non–Small Cell Lung Cancer”,就针对晚期非小细胞肺癌患者PD-L1表达状态与接受免疫检测点抑制剂治疗的情况做了...
免疫检查点与PD-1/PD-L1抗体 ImmunecheckpointandPD-1/PD-L1antibody 3 PD-1/PD-L1抑制剂现状 CurrentstatusofPD-1/PD-L1inhibitors 4 问题与展望 ProblemsandProspects 肿瘤免疫治疗TumorImmunotherapy 肿肿瘤瘤免免疫疫疗疗法法的的分现类状 肿瘤免疫疗法的原理和分类PrinciplesandClassificationofTumorImmunotherapy 1...
Multivariate Cox regression analysis showed that Eastern Cooperative Oncology Group performance status score and steroid/antibacterial drug exposure during immunotherapy were independent predictors of PFS in patients with gastrointestinal cancer after anti-PD-1/PD-L1 treatment. The...
Patients with higher circulating senescent T cells were more likely to be BRCA-negative and have intermediate levels of tumor-infiltrating lymphocytes. There was no correlation between exhausted T cells and BRCA status or the...