Full Name CD274 molecule Synonyms CD274, PD-L1, PD L1, hPD-L1, B7-H1 Calculated Molecular Weight 290 aa, 33 kDa Observed Molecular Weight 45-50 kDa GenBank Accession Number BC074984 Gene Symbol PD-L1 Gene ID (NCBI) 29126 RRID AB_3671214 Conjugate Unconjugated Form Liquid Purification Meth...
Full Name CD274 antigen Synonyms Cd274, PD-L1, Pdcd1lg1, Pdcd1l1, PD L1 GenBank Accession Number BC066841 Gene Symbol PD-L1 Gene ID (NCBI) 60533 RRID AB_2882973 Conjugate APC Fluorescent Dye Excitation/Emission Maxima Wavelengths 650 nm / 660 nm Form Liquid Purification Method Affinity pu...
Full Name CD274 molecule Calculated Molecular Weight 290 aa, 33 kDa Observed Molecular Weight 45-50 kDa, 33 kDa GenBank Accession Number BC074984 Gene Symbol PD-L1 Gene ID (NCBI) 29126 RRID AB_2756526 Conjugate Unconjugated Form Liquid Purification Method Protein A purification UNIPROT ID Q9NZ...
Full Name CD274 molecule Calculated Molecular Weight 290 aa, 33 kDa Observed Molecular Weight 45-56 kDa, 65-70 kDa GenBank Accession Number BC074984 Gene Symbol PD-L1 Gene ID (NCBI) 29126 RRID AB_10597552 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification UNIPROT...
The current paradigm is that full activation of T cells requires at least 2 signals upon contact with antigen-presenting cells (APCs) [1, 2]. Signal 1 is delivered through the interaction of the T cell receptor (TCR) and a specific antigenic peptide associated with an MHC (major ...
Please see full U.S. Prescribing Information including the U.S. Medication Guide . About BeiGene BeiGene, which plans to change its name to BeOne Medicines Ltd., is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to ...
Full size image Roles of PD-1/PD-L1 in transplantation and autoimmune diseases The PD-1/PD-L1 signaling pathway is critical in autoimmune diseases, viral infections, transplantation and tumor immunity [32,33]. Under a normal physiologic state, PD-1/PD-L1 signaling can effectively inhibit the ...
Anti-PD-L1 Antibody (FITC) (Mouse Monoclonal antibody) General InformationProduct name Anti-PD-L1 Antibody (FITC) Validated applications FCM Species reactivity Reacts with: Human Specificity Human PD-L1 Immunogen Recombinant Human PD-L1/B7-H1/CD274 Protein (Catalog#10084-H08H) Preparation ...
Full size image Double-staining IHC analysis revealed that CAFs expressed PlGF/VEGF receptors (Fig.2g), and NRP1+CAF, VR1+CAF, and VR2+CAF were strongly negatively correlated with patient prognosis (r = −0.7199,p < 0.001;r = −0.6898,p < 0.001;r = −0.7131...
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